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What is the best initial therapy for patients with uninvestigated heartburn?

Nature Clinical Practice Gastroenterology & Hepatology volume 2, pages 394–395 (2005)Cite this article

boxed-textArmstrong D et al. (2005) Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPIstart' and 'H2RA-start' management strategies in primary care—the CADET-HR study. Aliment Pharmacol Ther 21: 1189–1202

Omeprazole provides faster and more effective initial control of heartburn symptoms in uninvestigated dyspepsia than ranitidine; however, 41% of patients can be treated with ranitidine alone

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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  1. Family Practitioner and Professor of Primary Care at the University of Birmingham, Birmingham, UK

    Brendan C Delaney

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  1. Brendan C Delaney
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Correspondence to Brendan C Delaney.

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Competing interests

BC Delaney has received speaker's honoraria from Astra Zeneca, Wyeth, Takeda, AxCan and Beckitt-Benkiser.

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Delaney, B. What is the best initial therapy for patients with uninvestigated heartburn?. Nat Rev Gastroenterol Hepatol 2, 394–395 (2005). https://doi.org/10.1038/ncpgasthep0262

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