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Management of stress-related bleeding: evolution from the era before cimetidine

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References

  1. Shuman RB et al. (1987) Prophylactic therapy for stress ulcer bleeding: a reappraisal. Ann Intern Med 106: 562–567

    Article  CAS  Google Scholar 

  2. Tryba M (1991) Prophylaxis of stress ulcer bleeding. A meta-analysis. J Clin Gastroenterol 13 (Suppl 2): S44–S55

    PubMed  Google Scholar 

  3. Cook D et al. (1998) A comparison of sucralfate and ranitidine for the prevention of upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group. N Engl J Med 338: 791–797

    Article  CAS  Google Scholar 

  4. Leontiadis GI (2005) Systematic review and meta-analysis of proton pump inhibitor therapy in peptic ulcer bleeding. Br Med J 12: 568–570

    Article  Google Scholar 

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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Correspondence to David A Peura.

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Competing interests

DA Peura has served as a consultant and speaker fpr Santarus, which markets immediate-release omeprazole (Zegerid®).

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Peura, D. Management of stress-related bleeding: evolution from the era before cimetidine. Nat Rev Gastroenterol Hepatol 2, 388–389 (2005). https://doi.org/10.1038/ncpgasthep0258

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