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Aberrant crypt foci as biomarkers for colonic dysplasia

Nature Clinical Practice Gastroenterology & Hepatology volume 2, pages 390–391 (2005)Cite this article

boxed-textHurlstone P et al. (2005) Rectal aberrant crypt foci identified using high-magnification chromoendoscopic colonoscopy: biomarkers for flat and depressed neoplasia. Am J Gastroenterol 100: 1283–1289

The ability to quantify aberrant crypt foci in clinical practice has the potential to enhance screening for colorectal cancer and identify high-risk individuals

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References

  1. Bird RP et al. (1987) Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen: preliminary findings. Cancer Lett 137: 147–151

    Article  Google Scholar 

  2. Takayama T et al. (1998) Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 339: 1277–1284

    Article  CAS  Google Scholar 

  3. Adler DG et al. (2002) Endoscopic identification and quantification of aberrant crypt foci in the human colon. Gastrointest Endosc 56: 657–662

    Article  Google Scholar 

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Acknowledgements

The synopsis was written by Rachel Jones, Associate Editor, Nature Clinical Practice.

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  1. Director of Gastrointestinal Endoscopy and Assistant Professor of Medicine at the University of Texas–Houston Medical School, Houston, TX, USA

    Douglas G Adler

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  1. Douglas G Adler
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Correspondence to Douglas G Adler.

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The author declares no competing financial interests.

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Adler, D. Aberrant crypt foci as biomarkers for colonic dysplasia. Nat Rev Gastroenterol Hepatol 2, 390–391 (2005). https://doi.org/10.1038/ncpgasthep0256

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