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Does a combined intravenous and subcutaneous insulin strategy improve outcomes after cardiothoracic surgery?

Nature Clinical Practice Endocrinology & Metabolism volume 3, pages 680–681 (2007)Cite this article

boxed-textSchmeltz LR et al. (2007) Reduction of surgical mortality and morbidity in diabetic patients undergoing cardiac surgery with a combined intravenous and subcutaneous insulin glucose management strategy. Diabetes Care 30: 823–828

Excessive hyperglycemia-associated mortality and morbidities can be avoided when intravenous insulin infusion is replaced by subcutaneous basal–prandial–correction insulin analog therapy at the time of patient transfer from the ICU

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References

  1. Brown JR et al. (2006) The diabetic disadvantage: historical outcomes measures in diabetic patients undergoing cardiac surgery—the pre-intravenous insulin era. Semin Thorac Cardiovasc Surg 18: 281–298

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Acknowledgements

The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.

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  1. Division of Endocrinology, University of North Carolina–Chapel Hill, 8027 Burnett-Womack CB 7172, 160 Dental Circle, Chapel Hill, NC 27599-7172, USA sbraithw@med.unc.edu

Authors and Affiliations

  1. SS Braithwaite is Clinical Professor of Medicine at the University of North Carolina–Chapel Hill, NC, USA.,

    Susan Shapiro Braithwaite

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  1. Susan Shapiro Braithwaite
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Competing interests

Dr Braithwaite's employing institution has received honoraria for her activities as a speaker for Sanofi-Aventis and as a consultant for Novo Nordisk. She has received support for clinical trials from Bristol-Myers Squibb.

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Braithwaite, S. Does a combined intravenous and subcutaneous insulin strategy improve outcomes after cardiothoracic surgery?. Nat Rev Endocrinol 3, 680–681 (2007). https://doi.org/10.1038/ncpendmet0589

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