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Does addition of gabapentin to antidepressant therapy improve control of hot flashes?

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References

  1. Nelson HD et al. (2006) Nonhormonal therapies for menopausal hot flashes: systematic review and meta-analysis. JAMA 295: 2057–2071

    Article  CAS  Google Scholar 

  2. MacLennan A et al. Oral estrogen replacement therapy versus placebo for hot flashes. Cochrane Database of Systematic Reviews 2004, Issue 4. Art. No.: CD002978.pub2. DOI:10.1002/14651858.CD002978.pub2.

    Google Scholar 

  3. Guttuso T Jr et al. (2003) Gabapentin's effects on hot flashes in postmenopausal women: a randomized controlled trial. Obstet Gynecol 101: 337–345

    CAS  PubMed  Google Scholar 

  4. Pandya KJ et al. (2005) Gabapentin for hot flashes in 420 women with breast cancer: a randomised double-blind placebo-controlled trial. Lancet 366: 818–824

    Article  CAS  Google Scholar 

  5. Reddy SY et al. (2006) Gabapentin, estrogen, and placebo for treating hot flushes: a randomized controlled trial. Obstet Gynecol 108: 41–48

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice.

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Consulting: Duramed, Novo Nordisk, Wyeth, and Merck. Research Funding: Solvay and Wyeth. Speakers Bureau: Duramed and Merck

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Pinkerton, J. Does addition of gabapentin to antidepressant therapy improve control of hot flashes?. Nat Rev Endocrinol 3, 566–567 (2007). https://doi.org/10.1038/ncpendmet0557

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