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How useful is autoantibody screening in adult-onset diabetes?

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References

  1. Turner R et al. (1997) UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet 350: 1288–1293

    Article  CAS  Google Scholar 

  2. Törn C et al. (2000) Glutamic acid decarboxylase antibodies (GADA) is the most important factor for prediction of insulin therapy within 3 years in young adult diabetic patients not classified as type 1 diabetes on clinical grounds. Diabetes Metab Res Rev 16: 442–447

    Article  Google Scholar 

  3. Monge L et al. (2004) A clinically orientated approach increases the efficiency of screening for latent autoimmune diabetes in adults (LADA) in a large clinic-based cohort of patients with diabetes onset over 50 years. Diabet Med 21: 456–459

    Article  CAS  Google Scholar 

  4. Juneja R et al. (2001) Islet cell antibodies and glutamic acid decarboxylase antibodies, but not the clinical phenotype, help to identify type 1(1/2) diabetes in patients presenting with type 2 diabetes. Metabolism 50: 1008–1013

    Article  CAS  Google Scholar 

  5. Borg H et al. (2002) A 12-year prospective study of the relationship between islet antibodies and β-cell function at and after the diagnosis in patients with adult-onset diabetes. Diabetes 51: 1754–1762

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Vicky Heath, Associate Editor, Nature Clinical Practice. LK Gilliam and JP Palmer are supported in part by grants from the medical Research Service of the Department of Veteran Affairs, GlaxoSmithKline, and NIH DK053004, DK17047 and RR00037.

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Correspondence to Lisa K Gilliam.

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Research supported by a grant from GlaxoSmithKline.

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Gilliam, L., Palmer, J. How useful is autoantibody screening in adult-onset diabetes?. Nat Rev Endocrinol 2, 490–491 (2006). https://doi.org/10.1038/ncpendmet0268

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