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Tracking translation one mRNA at a time

Nature Biotechnology volume 34, pages 723–724 (2016)Cite this article

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Imaging of single mRNA molecules undergoing translation provides insights into the regulation of protein synthesis.

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Figure 1: Strategy for imaging single mRNA molecules undergoing translation.

Kim Caesar/Nature Publishing Group

References

  1. Wu, B., Eliscovich, C., Yoon, Y. & Singer, R.H. Science doi:10.1126/science.aaf1084 (2016).

  2. Morisaki, T. et al. Science doi:10.1126/science.aaf0899 (2016).

  3. Yan, X., Hoek, T.A., Vale, R.D. & Tanenbaum, M.E. Cell 165, 976–989 (2016).

    Article  CAS  Google Scholar 

  4. Wang, C., Han, B., Zhou, R. & Zhuang, X. Cell 165, 990–1001 (2016).

    Article  CAS  Google Scholar 

  5. Ingolia, N.T., Ghaemmaghami, S., Newman, J.R. & Weissman, J.S. Science 324, 218–223 (2009).

    Article  CAS  Google Scholar 

  6. Ingolia, N.T., Lareau, L.F. & Weissman, J.S. Cell 147, 789–802 (2011).

    Article  CAS  Google Scholar 

  7. Bertrand, E. et al. Mol. Cell 2, 437–445 (1998).

    Article  CAS  Google Scholar 

  8. Wu, B., Chao, J.A. & Singer, R.H. Biophys. J. 102, 2936–2944 (2012).

    Article  CAS  Google Scholar 

  9. Garcia, J.F. & Parker, R. RNA 21, 1393–1395 (2015).

    Article  CAS  Google Scholar 

  10. Nelles, D.A. et al. Cell 165, 488–496 (2016).

    CAS  PubMed  PubMed Central  Google Scholar 

Download references

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Authors and Affiliations

  1. Jiahui Wu and Samie R. Jaffrey are in the Department of Pharmacology, Weill Cornell Medical College, Cornell University, New York, NY, USA.,

    Jiahui Wu & Samie R Jaffrey

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  1. Jiahui Wu
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  2. Samie R Jaffrey
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Correspondence to Samie R Jaffrey.

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The authors declare no competing financial interests.

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Wu, J., Jaffrey, S. Tracking translation one mRNA at a time. Nat Biotechnol 34, 723–724 (2016). https://doi.org/10.1038/nbt.3632

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