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Autoimmunity

Rubbing salt in the wound

Nature volume 496, pages 437439 (25 April 2013) | Download Citation

The ability of sodium chloride to induce enzymatic activity that leads to the generation of pathogenic TH17 immune cells implicates salt as a possible factor that might exacerbate autoimmune disease. See Letters p.513 & p.518

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Author information

Affiliations

  1. John J. O'Shea is in the Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, Maryland 20892-1616, USA.

    • John J. O'Shea
  2. Russell G. Jones is at the Rosalind and Morris Goodman Cancer Research Centre, Department of Physiology, McGill University, Montreal, Quebec H3G 1Y6, Canada.

    • Russell G. Jones

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Corresponding authors

Correspondence to John J. O'Shea or Russell G. Jones.

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https://doi.org/10.1038/nature11959

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