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  • TECHNOLOGY FEATURE

Every base everywhere all at once: pangenomics comes of age

Multi-genome assemblies called pangenomes can capture genetic diversity in a species, but researchers are still working out how best to build and explore them.
  1. Michael Eisenstein

    1. Michael Eisenstein is a freelance writer based in Philadelphia, Pennsylvania.

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The word ‘reference’ conveys authority, signifying a trusted resource against which new information can confidently be assessed. That was true of encyclopaedias and atlases, and it’s true of reference genomes — ultra-high-accuracy maps that describe the complete sequence of a species’ chromosomal DNA.

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Nature 616, 618-620 (2023)

doi: https://doi.org/10.1038/d41586-023-01300-w

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