TECHNOLOGY FEATURE
09 May 2022

Methods combine to decode the biology of tuberculosis

Scientists are fusing sequencing, chemistry and imaging techniques to probe interactions between pathogens and their host cells.

Amber Dance⁰

Amber Dance
1. Amber Dance is a freelance writer in Los Angeles, California.
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Coloured scanning electron micrograph of tuberculosis bacteria invading white blood cells — *Mycobacterium tuberculosis* (orange) invades immune cells known as macrophages (pink) in the lungs. Credit: Science Photo Library

Tuberculosis has been a scourge of humanity for millennia: the oldest known cases are in a pair of 9,000-year-old skeletons. Despite modern therapies, the disease affects about ten million people a year. It’s challenging both to treat, and to study in the laboratory.

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Nature 605, 385-386 (2022)

doi: https://doi.org/10.1038/d41586-022-01260-7

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