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  • TECHNOLOGY FEATURE

The microscope makers

A small community of scientists has taken a do-it-yourself approach to microscopy: when the right tool for the job doesn’t exist, make it.
  1. Brian Owens

    1. Brian Owens is a freelance science writer based in New Brunswick, Canada.

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While pursuing a bioengineering PhD at the University of Pennsylvania in Philadelphia, Wesley Legant ran into a frustrating roadblock: he had ideas, but the equipment to carry them out didn’t yet exist.

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Nature 551, 659-662 (2017)

doi: https://doi.org/10.1038/d41586-017-07528-7

References

  1. Legant, W. R. et al. Nature Methods 7, 969–971 (2010).

    Article  PubMed  CAS  Google Scholar 

  2. Keller, P. J., Schmidt, A. D., Wittbrodt, J. & Stelzer, E. H. K. Science 322, 1065–1069 (2008).

    Article  PubMed  CAS  Google Scholar 

  3. Klar, T. A., Jakobs, S., Dyba, M., Egner, A. & Hell, S. W. Proc. Natl Acad. Sci. USA 97, 8206–8210 (2000).

    Article  PubMed  CAS  Google Scholar 

  4. Salmon, E. D. & Waterman, C. M. Mol. Biol. Cell 22, 3940–3942 (2011).

    Article  PubMed  CAS  Google Scholar 

  5. Chhetri, R. K. et al. Nature Methods 12, 1171–1178 (2015).

    Article  PubMed  CAS  Google Scholar 

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