Brief Communication | Published:

Genome evolution

Gene capture in archaeal chromosomes

Nature volume 409, page 478 (25 January 2001) | Download Citation

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Abstract

Free genetic elements can be readily integrated into bacterial chromosomes, but so far, with the exception of one virus, there has been no evidence that this happens in Archaea — the other domain of microorganisms. Here we show that site-specific integration of different genetic elements into archaeal chromosomes is a general phenomenon, albeit rare, which requires an archaeal integrase and produces a partitioned integrase gene in the chromosome. The process is distinct from bacterial mechanisms and has implications for how horizontal gene transfer might occur across the boundaries of the domains of life.

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Affiliations

  1. *Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen K, Denmark

    • Qunxin She
    • , Xu Peng
    •  & Roger A. Garrett
  2. †Max-Planck-Institut für Biochemie, D-82152 Martinsried, Germany

    • Wolfram Zillig

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DOI

https://doi.org/10.1038/35054138

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