The establishment of Spemmann's organizer and patterning of the vertebrate embryo.

De Robertis, E. M. et al. Nature Reviews Genetics December(2000). http://www.nature.com/nrg

How to form a vesicle.

Kirchhausen, T. Nature Reviews Molecular Cell Biology December (2000). http://www.nature.com/ncb/

p63 and p73: p53 mimics, menaces and more.

Yang A. & McKeon, F. Nature Reviews Molecular Cell Biology December (2000). http://www.nature.com/ncb/

Intramembranous proteolysis by presenilins.

Steiner, H. & Haass, C. Nature Reviews Molecular Cell Biology December (2000). http://www.nature.com/ncb/

A News and Views article on the development of a new animal model for Parkinson's disease.

Real brains for real robots

Mussa-Ivaldi, S. Nature 16 November (2000). http://www.nature.com/nature/

A News and Views article on the attempts to predict arm trajectory using ensembles of cortical neurons.

Dissecting the ins and outs of excitement: glutamate receptors on the move.

Haucke, V. Nature Neuroscience December (2000). http://www.nature.com/neuro

A News and Views article on recent findings about the regulation of AMPA-receptor endocytosis at excitatory synapses

Feedback control of intercellular signalling in development.

Freeman. M. Nature 16 November (2000). http://www.nature.com/nature/

The intercellular communication that regulates cell fate during development must be under precise control. How is this control achieved?

Paxilin and focal adhesion signalling.

Turner, C. E. Nature Cell Biology December (2000). http://www.nature.com/ncb/

Computational approaches to brain function.

Special supplement to Nature Neuroscience November (2000). http://www.nature.com/neuro

New link between pesticides and Parkinson's disease. Glasson, B. I. & Lee, V. M. -Y. Nature Neuroscience December (2000).