Experimental production of diabetes mellitus by a nonendocrinal approach

Abstract

THE immunofluorescent demonstration of large deposits of fibrin in the microvascular lesions1,2, and evidence of a slow consumptive fibrinocoagulopathy in maturity onset diabetes mellitus3,4, suggested the possibility of a primary fibrinocoagulopathic vascular aetiopathogenesis of the disorder. The present work was undertaken to investigate the possibility of an experimental production of diabetes mellitus in animals by induction of slow consumptive fibrinocoagulopathy.

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BANERJEE, R., RAO, S. & BARDHAN, J. Experimental production of diabetes mellitus by a nonendocrinal approach. Nature 251, 51–53 (1974). https://doi.org/10.1038/251051a0

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