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Evidence for Heterogeneity of 23S RNA in E. coli

Abstract

CISTRONS for ribosomal RNA (rRNA) in bacteria exist in multiple copies1–3. There is therefore genetic potential for several molecular types of 16S and 23S rRNA. Recently, Young4 has reported evidence for such heterogeneity in Escherichia coli rRNA. We wish to report evidence of a different nature that such heterogeneity exists. This evidence has been obtained by electrophoresis on density gradient polyacrylamide gels and by stepwise elution from methylated albumin kieselguhr (MAK) columns.

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References

  1. Yankofsky, S. A., and Spiegelman, S., Proc. US Nat. Acad. Sci., 48, 1466 (1962).

    Article  ADS  CAS  Google Scholar 

  2. Yankofsky, S. A., and Spiegelman, S., Proc. US Nat. Acad. Sci., 49, 538 (1963).

    Article  ADS  CAS  Google Scholar 

  3. Oishi, M., and Sueoka, N., Proc. US Nat. Acad. Sci., 54, 483 (1965).

    Article  ADS  CAS  Google Scholar 

  4. Young, R. F., Fed. Proc., 27, 460 (1968).

    Google Scholar 

  5. Hayashi, M., and Spiegelman, S., Proc. US Nat. Acad. Sci., 47, 1564 (1961).

    Article  ADS  CAS  Google Scholar 

  6. Hastings, J. R. B., Parish, J. H., Kirby, K. S., and Klucis, E. S., Nature, 208, 645 (1965).

    Article  ADS  CAS  Google Scholar 

  7. Salo, T., and Kouns, D. M., Anal. Biochem., 13, 74 (1965).

    Article  CAS  Google Scholar 

  8. Loening, V. E., Biochemistry., 102, 251 (1967).

    Article  CAS  Google Scholar 

  9. Richards, E. G., Coll, J. A., and Gratzer, W. B., Anal. Biochem., 12, 452 (1965).

    Article  CAS  Google Scholar 

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SCHAUP, H., BEST, J. & GOODMAN, A. Evidence for Heterogeneity of 23S RNA in E. coli. Nature 221, 864–865 (1969). https://doi.org/10.1038/221864a0

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  • DOI: https://doi.org/10.1038/221864a0

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