Abstract
THE role of red blood cell group antigens in human histocompatibility has long been a matter of controversy1–6. It has recently been noted by Griffiths and Crikelair7, and by Kuhns, Rapaport et al.8, that a rise in anti-A and anti-B antibodies may occur following the exchange of skin homografts between blood group-incompatible subjects. This communication describes a series of experiments which provide suggestive evidence that erythrocyte group antigens may, on suitable immunization of recipients, play a significant part in conditioning the response of these subjects to first-set skin homografts.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Shawan, H. K., Amer. J. Med. Sci., 157, 503 (1919).
Brown, J. B., and McDowell, F., Ann. Surg., 115, 1166 (1942).
Woodruff, M. F. A., Brit. J. Plast. Surg., 5, 238 (1952).
Rogers, B. O., Ann. N.Y. Acad. Sci., 64, 741 (1957).
Woodruff, M. F. A., in The Transplantation of Tissues and Organs, edit. by Thomas, Ch. C. (Springfield, 1960).
Hamburger, J., Vaysse, J., Crosnier, J., Auvert, J., and Dormont, J., Ann. N.Y. Acad. Sci., 99, 808 (1962).
Griffiths, jun., C. O., and Crikelair, G. F., Nature, 193, 186 (1962).
Kuhns, W. J., Rapaport, F. T., Lawrence, H. S., and Converse, J. M., Ann. N.Y. Acad. Sci., 120, 36 (1964).
Converse, J. M., and Rapaport, F. T., Ann. Surg., 143, 306 (1956).
Rapaport, F. T., and Converse, J. M., Ann. N.Y. Acad. Sci., 64, 836 (1957).
Rapaport, F. T., and Converse, J. M., Ann. Surg., 147, 273 (1958).
Rapaport, F. T., Thomas, L., Converse, J. M., and Lawrence, H. S., Ann. N.Y. Acad. Sci., 87, 217 (1960).
Rapaport, F. T., Lawrence, H. S., Thomas, L., Converse, J. M., Tillett, W. S., and Mulholland, J. H., J. Clin. Invest., 41, 2166 (1962).
Gorer, P. A., J. Pathol. Bacteriol., 47, 231 (1937).
Bogden, A. E., and Aftekman, P. M., Ann. N.Y. Acad. Sci., 97, 43 (1962).
Schierman, L. W., and Nordskog, A. W., Transplantation, 3, 44 (1965).
Dausset, J., C.R. Soc. Biol., 148, 1607 (1954).
Gurner, B. W., and Coombs, R. R. A., Vox Sang., 3, 13 (1958).
Nelken, D., Gurevitch, J., and Neuman, Z., J. Clin. Invest., 36, 749 (1957).
Szulman, A. E., J. Exp. Med., 3, 785 (1960).
Lawrence, H. S., Rapaport, F. T., Converse, J. M., and Tillett, W. S., J. Clin. Invest., 39, 185 (1960).
Dausset, J., Colombani, J., Feingold, N., and Rapaport, F. T., Nouv. Rev. Franç. Hemat., 5, 17 (1965).
Rood, J. J. van, and Leeuwen, A. van, J. Clin. Invest., 42, 1382 (1963).
Weerdt, ch. van der, Wiel-Dorfmeier, H. van, Engelfriet, C. P., and Loghem, J. J. van, Proc. Eighth Congr. Europ. Soc. Haemat. Wien, 1961 (Karger, Basle/New York, 1962).
Dausset, J., and Berg, P., Vox Sang., 8, 341 (1963).
Murray, J. E., Transplantation, 2, 47 (1964).
Starzl, T. E., Marchioro, T. L., Holmes, J. H., Hermann, G., Brittain, R. S., Stonington, O. H., Talmage, D. W., and Waddell, W. R., Surgery, 55, 195 (1964).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DAUSSET, J., RAPAPORT, F. Role of ABO Erthrocyte Groups in Human Histocompatibility Reactions. Nature 209, 209–211 (1966). https://doi.org/10.1038/209209a0
Issue Date:
DOI: https://doi.org/10.1038/209209a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.