Abstract
DESPITE much recent work on erythropoietin which has established the important part played by the humoral factor in erythropoiesis, participation of the nervous system in the regulation of erythropoiesis has not been established. In view of the report of Jacobson et al. 1 suggesting the renal production of erythropoietin, as well as the work of Nakayama2 that showed the effect of the bilateral section of splanchnic nerve in abolishing the decrease of renal blood-flow on loss of blood or anoxic anoxia, we performed a bilateral section of splanchnic nerve in rats to observe the effect on erythropoiesis.
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References
Jacobson, L. O., Goldwasser, E., Fried, W., and Plzak, L., Nature, 179, 633 (1957).
Nakayama, S., Respiration and Circulation, 7, 191 (1959) (in Japanese).
Gray, S., and Sterling, K., J. Clin. Invest., 29, 1614 (1950).
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TAKAKU, F., HIRASHIMA, K. & OKINAKA, S. Effect of the Bilateral Section of the Splanchnic Nerve on Erythropoiesis. Nature 191, 500–501 (1961). https://doi.org/10.1038/191500a0
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DOI: https://doi.org/10.1038/191500a0
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