Abstract
POWERFUL ganglion-blocking properties have been found in the diquaternary-amino-carbinols (I), -alkenes (II), -alkanes (III), -nitriles (IV), -ethers (V) and -esters (VI): R 1 and R 2 are phenyl or cyclohexyl groups in the compounds described in this communication, but preliminary results show that ganglion-blocking action also occurs when R 1 and R 2 are pyridyl or thienyl groups. and are fully substituted quaternary nitrogen atoms.
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ADAMSON, D., BILLINGHURST, J., GREEN, A. et al. New Series of Ganglion-blocking Agents. Nature 177, 523–524 (1956). https://doi.org/10.1038/177523a0
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DOI: https://doi.org/10.1038/177523a0
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