Abstract
A VARIETY of cells and tissues of mammals survive for long periods at the temperature of ‘dry ice’ − 79° C., when frozen in media containing glycerol1. At the other extreme, Andjus's work on the whole animal shows that, by special methods of cooling and rewarming, rats can be revived from deep body temperatures of about + 0.5° C.2. We are now attempting to close the gap between these two lines of work (a) by increasing the size and complexity of the isolated tissue cooled to − 79° C., as, for example, by freezing a whole isolated organ3, and (b) by reducing the whole animal to a body temperature below zero. This communication deals with experiments on the second of these developments.
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References
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Andjus, R. K., and Smith, A. U., J. Physiol., 123, 66P (1954).
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SMITH, A., LOVELOCK, J. & PARKES, A. Resuscitation of Hamsters after Supercooling or Partial Crystallization at Body Temperatures Below 0° C.. Nature 173, 1136–1137 (1954). https://doi.org/10.1038/1731136a0
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DOI: https://doi.org/10.1038/1731136a0
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