An Antibiotic from Spiræa aruncus L

Abstract

FOLLOWING the observation1 that a watery extract of leaves and flowers of Spiræa aruncus L. possesses antibacterial properties, the active substance has now been isolated from the plant in crystalline form. It has, however, very low activity, preventing the growth of Staph. aureus, B. proteus and B. coli in a dilution of only 1 in 4,000, and having no effect on Ps. pyocyanea at 1 in 2,000. In view of its low activity, the substance has not been investigated in detail, but it is perhaps worth putting on record the following results.

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References

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    Osborn, Brit. J. Exp. Path., 21, 227 (1943).

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    Jacobs and Hoffmann., J. Biol. Chem., 67, 336 (1926).

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    Thiele, Ann., 319, 144 (1901).

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ABRAHAM, E., HEATLEY, N., BOLT, R. et al. An Antibiotic from Spiræa aruncus L. Nature 157, 511 (1946). https://doi.org/10.1038/157511b0

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