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| Open AccessThe AP-1 transcription factor JunB is required for Th17 cell differentiation
- Soh Yamazaki
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| Open AccessThe conserved ancient role of chordate PIAS as a multilevel repressor of the NF-κB pathway
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| Open AccessHyaluronic acid 35 normalizes TLR4 signaling in Kupffer cells from ethanol-fed rats via regulation of microRNA291b and its target Tollip
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| Open AccessDifferential T Cell Signaling Pathway Activation by Tacrolimus and Belatacept after Kidney Transplantation: Post Hoc Analysis of a Randomised-Controlled Trial
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| Open AccessThe RNA binding protein La/SS-B promotes RIG-I-mediated type I and type III IFN responses following Sendai viral infection
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| Open AccessA model integrating tonic and antigen-triggered BCR signals to predict the survival of primary B cells
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| Open AccessNADPH oxidase 4 modulates hepatic responses to lipopolysaccharide mediated by Toll-like receptor-4
- Anand Singh
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| Open AccessTC-PTP regulates the IL-7 transcriptional response during murine early T cell development
- K. A. Pike
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| Open AccessSyk-dependent tyrosine phosphorylation of 3BP2 is required for optimal FcRγ-mediated phagocytosis and chemokine expression in U937 cells
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| Open AccessPepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
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| Open AccessMitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/β-catenin signaling
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| Open AccessA complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation
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| Open AccessCharacterization of the Mollusc RIG-I/MAVS Pathway Reveals an Archaic Antiviral Signalling Framework in Invertebrates
- Baoyu Huang
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| Open AccessPKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells
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| Open AccessSirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes
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| Open AccessAttenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway
- Xin Nie
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| Open AccessSystemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
- Xiuwen Wu
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| Open AccessHuman in vitro-induced regulatory T cells display Dlgh1 dependent and PKC-θ restrained suppressive activity
- Alexandra Zanin-Zhorov
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| Open AccessLoss of Gαi proteins impairs thymocyte development, disrupts T-cell trafficking, and leads to an expanded population of splenic CD4+PD-1+CXCR5+/− T-cells
- Il-Young Hwang
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| Open AccessTranscription Factor Forkhead Regulates Expression of Antimicrobial Peptides in the Tobacco Hornworm, Manduca sexta
- Xue Zhong
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| Open AccessRNAi Screen and Proteomics Reveal NXF1 as a Novel Regulator of IRF5 Signaling
- Bishi Fu
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| Open AccessLow level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun
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| Open AccessTRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22
- Alicia M. Wallis
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| Open AccessInhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo
- Hannah M. Komar
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| Open AccessBasal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88
- Takeshi Into
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| Open AccessNOD1 modulates IL-10 signalling in human dendritic cells
- Theresa Neuper
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| Open AccessMKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses
- Chanyoung Shin
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| Open AccessCrosstalk between signals initiated from TLR4 and cell surface BAFF results in synergistic induction of proinflammatory mediators in THP-1 cells
- Su-Geun Lim
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| Open AccessProtective effect of TM6 on LPS-induced acute lung injury in mice
- Xiaoyu Hu
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| Open AccessIdentification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response
- Haoyang Li
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| Open AccessA conformational change within the WAVE2 complex regulates its degradation following cellular activation
- Noah Joseph
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| Open AccessThe role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs
- Fabián Salazar
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| Open AccessResolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis
- Trudy McGarry
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| Open AccessChloroquine inhibits human CD4+ T-cell activation by AP-1 signaling modulation
- Ralf L. J. Schmidt
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| Open AccessMulti-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster
- Miju Kim
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| Open AccessClass B β-arrestin2-dependent CCR5 signalosome retention with natural antibodies to CCR5
- Assunta Venuti
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| Open AccessMycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses
- Monoranjan Boro
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| Open Accessβ-Arrestin 1’s Interaction with TC45 Attenuates Stat signaling by dephosphorylating Stat to inhibit antimicrobial peptide expression
- Jie-Jie Sun
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| Open AccessApocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state
- Silvia Cellone Trevelin
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| Open AccessMicrobial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses
- Kenneth Barth
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| Open AccessRegulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1
- Nobuko Matsushita
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| Open AccessDimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation
- Victoria A. McGuire
- , Tamara Ruiz-Zorrilla Diez
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| Open AccessSARS Coronavirus Fusion Peptide-Derived Sequence Suppresses Collagen-Induced Arthritis in DBA/1J Mice
- Zu T. Shen
- & Alexander B. Sigalov
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| Open AccessThe ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1
- Man He
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- & Deying Tian
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| Open AccessLRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation
- Keiko Morimoto
- , Yoshihiro Baba
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| Open AccessCell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses
- Yanchuan Li
- , Hui Wang
- & Shao-Cong Sun
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| Open AccessLeukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression
- Holly R. Foster
- , Elisabeth Fuerst
- & Grzegorz Woszczek
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| Open AccessInhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction
- Michelle Vincendeau
- , Kamyar Hadian
- & Daniel Krappmann
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| Open AccessBcl6 Sets a Threshold for Antiviral Signaling by Restraining IRF7 Transcriptional Program
- Feng Xu
- , Yanhua Kang
- & Liyun Shi