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Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages
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Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation
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In vitro kinase assay reveals ADP-heptose-dependent ALPK1 autophosphorylation and altered kinase activity of disease-associated ALPK1 mutants
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GRB2 dimerization mediated by SH2 domain-swapping is critical for T cell signaling and cytokine production
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IL-6/ERK signaling pathway participates in type I IFN-programmed, unconventional M2-like macrophage polarization
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The LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling
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IκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice
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A novel lipidic peptide with potential to promote balanced effector-regulatory T cell responses
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The impact of short-term confinement on human innate immunity
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Open label safety and efficacy pilot to study mitigation of equine recurrent uveitis through topical suppressor of cytokine signaling-1 mimetic peptide
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Ionic mitigation of CD4+ T cell metabolic fitness, Th1 central nervous system autoimmunity and Th2 asthmatic airway inflammation by therapeutic zinc
- Anna Krone
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Tunable heat shock protein-mediated NK cell responses are orchestrated by STAT1 in Antigen Presenting Cells
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Verloren negatively regulates the expression of IMD pathway dependent antimicrobial peptides in Drosophila
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Cholesterol-dependent plasma membrane order (Lo) is critical for antigen-specific clonal expansion of CD4+ T cells
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Suppression of human T cell activation by derivatives of glycerol monolaurate
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TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS
- Cécile Rittore
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Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function
- Matthew Stephens
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T cell signaling and Treg dysfunction correlate to disease kinetics in IL-2Rα-KO autoimmune mice
- Genevieve N. Mullins
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HIV-1 Tat – TLR4/MD2 interaction drives the expression of IDO-1 in monocytes derived dendritic cells through NF-κB dependent pathway
- Elmostafa Bahraoui
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Snellenius manilae bracovirus suppresses the host immune system by regulating extracellular adenosine levels in Spodoptera litura
- Yuan Chang
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Development of hypoallergenic variants of the major horse allergen Equ c 1 for immunotherapy by rational structure based engineering
- Jaana Haka
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Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells
- Trine B. Levring
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Preventative and Therapeutic Effects of Low-dose Ionizing Radiation on the Allergic Response of Rat Basophilic Leukemia Cells
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IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
- L. A. Freihat
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Role of NF-kappaB2-p100 in regulatory T cell homeostasis and activation
- Atika Dhar
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Putative link between Polo-like kinases (PLKs) and Toll-like receptor (TLR) signaling in transformed and primary human immune cells
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TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells
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Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling
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Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells
- Monika Raab
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Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling
- Charlotte M. Flynn
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HSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells
- Assunta Venuti
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Elevated pre-activation basal level of nuclear NF-κB in native macrophages accelerates LPS-induced translocation of cytosolic NF-κB into the cell nucleus
- Alexander V. Bagaev
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USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression
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Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis
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Endogenous Neurosteroid (3α,5α)3-Hydroxypregnan-20-one Inhibits Toll-like-4 Receptor Activation and Pro-inflammatory Signaling in Macrophages and Brain
- Irina Balan
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Cryopreservation of primary B cells minimally influences their signaling responses
- Johanne U. Hermansen
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ROCK2, but not ROCK1 interacts with phosphorylated STAT3 and co-occupies TH17/TFH gene promoters in TH17-activated human T cells
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Ageratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis
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Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases
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MyD88 signaling causes autoimmune sialadenitis through formation of high endothelial venules and upregulation of LTβ receptor-mediated signaling
- Takeshi Into
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Polarity of CD4+ T cells towards the antigen presenting cell is regulated by the Lck adapter TSAd
- Greger Abrahamsen
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Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells
- Kazumi Ebine
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TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway
- Jun Wang
- , Ricardo Ferreira
- & John R. Bradley
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Butyrate produced by gut commensal bacteria activates TGF-beta1 expression through the transcription factor SP1 in human intestinal epithelial cells
- Camille Martin-Gallausiaux
- , Fabienne Béguet-Crespel
- & Nicolas Lapaque
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Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells
- Shuzo Teruya
- , Tomohisa Okamura
- & Keishi Fujio
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Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation
- Van Ngo Thai Bich
- , Tsunaki Hongu
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The Cish SH2 domain is essential for PLC-γ1 regulation in TCR stimulated CD8+ T cells
- Geoffrey Guittard
- , Ana Dios-Esponera
- & Lawrence E. Samelson
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Impedance-based analysis of Natural Killer cell stimulation
- Frank Fasbender
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Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation
- Nassima Chouaki Benmansour
- , Kilian Ruminski
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Dynamic hydrogen peroxide levels reveal a rate-dependent sensitivity in B-cell lymphoma signaling