NF-kappaB articles within Scientific Reports

Featured

• Article
  08 July 2022 | Open Access

  IκBζ regulates the development of nonalcoholic fatty liver disease through the attenuation of hepatic steatosis in mice

  • Hideki Ishikawa
  • , Morisada Hayakawa
  •  & Tsukasa Ohmori

• Article
  18 February 2021 | Open Access

  TNFR1-d2 carrying the p.(Thr79Met) pathogenic variant is a potential novel actor of TNFα/TNFR1 signalling regulation in the pathophysiology of TRAPS

  • Cécile Rittore
  • , Déborah Méchin
  •  & Sylvie Grandemange

• Article
  14 January 2021 | Open Access

  Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function

  • Matthew Stephens
  • , Shan Liao
  •  & Pierre-Yves von der Weid

• Article
  29 October 2019 | Open Access

  IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity

  • L. A. Freihat
  • , J. I. Wheeler
  •  & H. R. Irving

• Article
  25 September 2019 | Open Access

  Role of NF-kappaB2-p100 in regulatory T cell homeostasis and activation

  • Atika Dhar
  • , Meenakshi Chawla
  •  & Soumen Basak

• Article
  18 July 2019 | Open Access

  Immune adaptor SKAP1 acts a scaffold for Polo-like kinase 1 (PLK1) for the optimal cell cycling of T-cells

  • Monika Raab
  • , Klaus Strebhardt
  •  & Christopher E. Rudd

• Article
  26 March 2019 | Open Access

  HSV-1\EGFP stimulates miR-146a expression in a NF-κB-dependent manner in monocytic THP-1 cells

  • Assunta Venuti
  • , Maria Musarra-Pizzo
  •  & Maria Teresa Sciortino

• Article
  14 March 2019 | Open Access

  Elevated pre-activation basal level of nuclear NF-κB in native macrophages accelerates LPS-induced translocation of cytosolic NF-κB into the cell nucleus

  • Alexander V. Bagaev
  • , Anastasiya Y. Garaeva
  •  & Fazly I. Ataullakhanov

• Article
  30 October 2018 | Open Access

  Ageratina adenophora induces mice hepatotoxicity via ROS-NLRP3-mediated pyroptosis

  • Wei Sun
  • , Chaorong Zeng
  •  & Yanchun Hu

• Article
  13 August 2018 | Open Access

  TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway

  • Jun Wang
  • , Ricardo Ferreira
  •  & John R. Bradley

• Article
  09 March 2018 | Open Access

  NF-κB is weakly activated in the NOD mouse model of type 1 diabetes

  • Allison E. Irvin
  • , Gaurang Jhala
  •  & Thomas W. H. Kay

• Article
  06 December 2017 | Open Access

  The conserved ancient role of chordate PIAS as a multilevel repressor of the NF-κB pathway

  • Ruihua Wang
  • , Shengfeng Huang
  •  & Anlong Xu

• Article
  23 August 2017 | Open Access

  Mitigation of sepsis-induced inflammatory responses and organ injury through targeting Wnt/β-catenin signaling

  • Archna Sharma
  • , Weng-Lang Yang
  •  & Ping Wang

• Article
  26 July 2017 | Open Access

  PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells

  • Khaled Alharshawi
  • , Alejandra Marinelarena
  •  & Bellur S. Prabhakar

• Article
  25 July 2017 | Open Access

  Sirt1 negatively regulates FcεRI-mediated mast cell activation through AMPK- and PTP1B-dependent processes

  • Xian Li
  • , Youn Ju Lee
  •  & Hyeun Wook Chang

• Article
  05 July 2017 | Open Access

  Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway

  • Xin Nie
  • , Shao-Ru Chen
  •  & Guo-Chun Zhou

• Article
  29 June 2017 | Open Access

  Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption

  • Xiuwen Wu
  • , Jianan Ren
  •  & Jieshou Li

• Article
  05 April 2017 | Open Access

  MKRN2 is a novel ubiquitin E3 ligase for the p65 subunit of NF-κB and negatively regulates inflammatory responses

  • Chanyoung Shin
  • , Yuma Ito
  •  & Takashi Tanaka

• Article
  04 April 2017 | Open Access

  Crosstalk between signals initiated from TLR4 and cell surface BAFF results in synergistic induction of proinflammatory mediators in THP-1 cells

  • Su-Geun Lim
  • , Jae-Kwan Kim
  •  & Won-Ha Lee

• Article
  31 March 2017 | Open Access

  Identification of two p53 isoforms from Litopenaeus vannamei and their interaction with NF-κB to induce distinct immune response

  • Haoyang Li
  • , Sheng Wang
  •  & Chaozheng Li

• Article
  03 March 2017 | Open Access

  The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs

  • Fabián Salazar
  • , Dennis Awuah
  •  & Amir M. Ghaemmaghami

• Article
  22 February 2017 | Open Access

  Resolution of TLR2-induced inflammation through manipulation of metabolic pathways in Rheumatoid Arthritis

  • Trudy McGarry
  • , Monika Biniecka
  •  & Ursula Fearon

• Article
  04 October 2016 | Open Access

  Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

  • Silvia Cellone Trevelin
  • , Célio Xavier dos Santos
  •  & Fernando Queiroz Cunha

• Article
  12 August 2016 | Open Access

  Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1

  • Nobuko Matsushita
  • , Midori Suzuki
  •  & Shigeru Yanagi

• Article
  08 August 2016 | Open Access

  Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

  • Victoria A. McGuire
  • , Tamara Ruiz-Zorrilla Diez
  •  & J. Simon C. Arthur

• Article
  08 June 2016 | Open Access

  The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1

  • Man He
  • , Min Wang
  •  & Deying Tian

• Article
  11 May 2016 | Open Access

  LRRK1 is critical in the regulation of B-cell responses and CARMA1-dependent NF-κB activation

  • Keiko Morimoto
  • , Yoshihiro Baba
  •  & Atsushi Kumanogoh

• Article
  07 January 2016 | Open Access

  Inhibition of Canonical NF-κB Signaling by a Small Molecule Targeting NEMO-Ubiquitin Interaction

  • Michelle Vincendeau
  • , Kamyar Hadian
  •  & Daniel Krappmann

• Article
  18 December 2015 | Open Access

  PDLIM1 inhibits NF-κB-mediated inflammatory signaling by sequestering the p65 subunit of NF-κB in the cytoplasm

  • Rumiko Ono
  • , Tsuneyasu Kaisho
  •  & Takashi Tanaka

• Article
  24 August 2015 | Open Access

  STAT1 deficiency redirects IFN signalling toward suppression of TLR response through a feedback activation of STAT3

  • Hun Sik Kim
  • , Dong Chan Kim
  •  & Go-Eun Choi

• Article
  04 August 2015 | Open Access

  USP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms

  • Zhifen Yang
  • , Huifang Xian
  •  & Jun Cui

• Article
  28 July 2015 | Open Access

  Transmembrane protein 106a activates mouse peritoneal macrophages via the MAPK and NF-κB signaling pathways

  • Hui Dai
  • , Dong Xu
  •  & Yingyu Chen

• Article
  12 June 2015 | Open Access

  Vitamin D3 inhibits lipopolysaccharide-induced placental inflammation through reinforcing interaction between vitamin D receptor and nuclear factor kappa B p65 subunit

  • Yuan-Hua Chen
  • , Zhen Yu
  •  & De-Xiang Xu

• Article
  10 January 2014 | Open Access

  Pharmacologic IKK/NF-κB inhibition causes antigen presenting cells to undergo TNFα dependent ROS-mediated programmed cell death

  • Jeremy S. Tilstra
  • , Daniel F. Gaddy
  •  & Paul D. Robbins

• Article
  06 September 2013 | Open Access

  Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway

  • Noritaka Yamaguchi
  • , Masaaki Oyama
  •  & Jun-ichiro Inoue