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| Open Accessα-Synuclein promotes IAPP fibril formation in vitro and β-cell amyloid formation in vivo in mice
- Marija Mucibabic
- , Pär Steneberg
- & Helena Edlund
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| Open AccessCMT-3 targets different α-synuclein aggregates mitigating their toxic and inflammogenic effects
- Florencia González-Lizárraga
- , Diego Ploper
- & Rosana Chehín
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| Open AccessBenefits and constrains of covalency: the role of loop length in protein stability and ligand binding
- Sara Linse
- , Eva Thulin
- & Johannes Stigler
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| Open AccessReproductive potential does not cause loss of heat shock response performance in honey bees
- S. R. Shih
- , E. M. Huntsman
- & J. W. Snow
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| Open AccessThe secondary structural difference between Lewy body and glial cytoplasmic inclusion in autopsy brain with synchrotron FTIR micro-spectroscopy
- Katsuya Araki
- , Naoto Yagi
- & Hideki Mochizuki
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| Open AccessSampling of the conformational landscape of small proteins with Monte Carlo methods
- Nana Heilmann
- , Moritz Wolf
- & Wolfgang Wenzel
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| Open AccessToxic oligomers of the amyloidogenic HypF-N protein form pores in mitochondrial membranes
- Maria Ylenia Farrugia
- , Mario Caruana
- & Neville Vassallo
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| Open AccessDistribution of disease-causing germline mutations in coiled-coils implies an important role of their N-terminal region
- Zsofia E. Kalman
- , Bálint Mészáros
- & Laszlo Dobson
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| Open AccessIodine staining as a useful probe for distinguishing insulin amyloid polymorphs
- Takato Hiramatsu
- , Naoki Yamamoto
- & Eri Chatani
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| Open AccessSolution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches
- John F. Darby
- , Lewis R. Vidler
- & Paul Workman
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| Open AccessEfficiency of the four proteasome subtypes to degrade ubiquitinated or oxidized proteins
- Joanna Abi Habib
- , Etienne De Plaen
- & Benoit J. Van den Eynde
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Article
| Open AccessNetwork Hamiltonian models reveal pathways to amyloid fibril formation
- Yue Yu
- , Gianmarc Grazioli
- & Carter T. Butts
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| Open AccessIdentification of pathogenic missense mutations using protein stability predictors
- Lukas Gerasimavicius
- , Xin Liu
- & Joseph A. Marsh
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| Open AccessGallic acid oxidation products alter the formation pathway of insulin amyloid fibrils
- Andrius Sakalauskas
- , Mantas Ziaunys
- & Vytautas Smirnovas
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| Open AccessA novel fusion based on the evolutionary features for protein fold recognition using support vector machines
- Mohammad Saleh Refahi
- , A. Mir
- & Jalal A. Nasiri
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| Open AccessChemogenomic screening identifies the Hsp70 co-chaperone DNAJA1 as a hub for anticancer drug resistance
- Nitika
- , Jacob S. Blackman
- & Andrew W. Truman
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| Open AccessDifferential protein expression in diverse brain areas of Parkinson’s and Alzheimer’s disease patients
- A. R. Esteves
- & S. M. Cardoso
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| Open AccessStructure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms
- Christopher Selleck
- , Marcelo Monteiro Pedroso
- & Gerhard Schenk
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Article
| Open AccessCigarette smoke induces endoplasmic reticulum stress and suppresses efferocytosis through the activation of RhoA
- Hiroyuki Ito
- , Yoshiro Yamashita
- & Konosuke Morimoto
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| Open AccessPresence of intrinsically disordered proteins can inhibit the nucleation phase of amyloid fibril formation of Aβ(1–42) in amino acid sequence independent manner
- Koki Ikeda
- , Shota Suzuki
- & Hidekazu Hiroaki
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Article
| Open Access1.2 MV/cm pulsed electric fields promote transthyretin aggregate degradation
- Gen Urabe
- , Takashi Sato
- & Sunao Katsuki
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Article
| Open AccessGenome-wide identification and characterization of Solanum tuberosum BiP genes reveal the role of the promoter architecture in BiP gene diversity
- Venura Herath
- , Mathieu Gayral
- & Jeanmarie Verchot
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| Open AccessRescue of mutant gonadotropin-releasing hormone receptor function independent of cognate receptor activity
- Emery Smith
- , Jo Ann Janovick
- & Timothy P. Spicer
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Article
| Open AccessCyclophilin D binds to the acidic C-terminus region of α-Synuclein and affects its aggregation characteristics
- James Torpey
- , Jillian Madine
- & Lu-Yun Lian
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| Open AccessHigh expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition
- Quentin Tavernier
- , Antoine Legras
- & Nicolas Pallet
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| Open AccessMechanical unfolding of a knotted protein unveils the kinetic and thermodynamic consequences of threading a polypeptide chain
- Maira Rivera
- , Yuxin Hao
- & Mauricio Baez
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| Open AccessA single dose of eHSP72 attenuates sepsis severity in mice
- Maicon Machado Sulzbacher
- , Lucas Machado Sulzbacher
- & Thiago Gomes Heck
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| Open AccessCell-free expression tools to study co-translational folding of alpha helical membrane transporters
- Nicola J. Harris
- , Grant A. Pellowe
- & Paula J. Booth
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| Open AccessUltra-rapid glutathionylation of chymotrypsinogen in its molten globule-like conformation: A comparison to archaeal proteins
- Alessio Bocedi
- , Giorgia Gambardella
- & Giorgio Ricci
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| Open AccessOn the Aggregation and Nucleation Mechanism of the Monoclonal Antibody Anti-CD20 Near Liquid-Liquid Phase Separation (LLPS)
- Elvira Pantuso
- , Teresa F. Mastropietro
- & Gianluca Di Profio
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| Open AccessCo-chaperones DNAJA1 and DNAJB6 are critical for regulation of polyglutamine aggregation
- Claudio Rodríguez-González
- , Shiying Lin
- & Christian Hansen
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| Open AccessProteomics-Based Approach Identifies Altered ER Domain Properties by ALS-Linked VAPB Mutation
- Tomoyuki Yamanaka
- , Risa Nishiyama
- & Nobuyuki Nukina
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| Open AccessPresenting a codon-optimized palette of fluorescent proteins for use in Candida albicans
- Wouter Van Genechten
- , Liesbeth Demuyser
- & Patrick Van Dijck
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| Open AccessPolymorphic Aβ42 fibrils adopt similar secondary structure but differ in cross-strand side chain stacking interactions within the same β-sheet
- Hongsu Wang
- , Lan Duo
- & Zhefeng Guo
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| Open AccessFormation of distinct prion protein amyloid fibrils under identical experimental conditions
- Mantas Ziaunys
- , Tomas Sneideris
- & Vytautas Smirnovas
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| Open AccessSelective Binding of HSC70 and its Co-Chaperones to Structural Hotspots on CFTR
- Imad Baaklini
- , Conrado de Campos Gonçalves
- & Jason C. Young
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Article
| Open AccessTaurine Induces an Ordered but Functionally Inactive Conformation in Intrinsically Disordered Casein Proteins
- Mohd Younus Bhat
- , Laishram Rajendrakumar Singh
- & Tanveer Ali Dar
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| Open AccessEvaluating the significance of contact maps in low-homology protein modeling using contact-assisted threading
- Sutanu Bhattacharya
- & Debswapna Bhattacharya
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| Open AccessN-terminal domain of the architectural protein CTCF has similar structural organization and ability to self-association in bilaterian organisms
- Artem Bonchuk
- , Sofia Kamalyan
- & Pavel Georgiev
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| Open AccessAssessment of recombinant protein production in E. coli with Time-Gated Surface Enhanced Raman Spectroscopy (TG-SERS)
- Martin Kögler
- , Jaakko Itkonen
- & Marco G. Casteleijn
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| Open AccessEndoplasmic reticulum stress promotes inflammation-mediated proteolytic activity at the ocular surface
- Ashley M. Woodward
- , Antonio Di Zazzo
- & Pablo Argüeso
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| Open AccessAssembly and Folding Properties of Cytosolic IgG Intrabodies
- Youngsil Seo
- , Yeonjin Lee
- & Myung-Hee Kwon
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| Open AccessProtein stability governed by its structural plasticity is inferred by physicochemical factors and salt bridges
- Anindya S. Panja
- , Smarajit Maiti
- & Bidyut Bandyopadhyay
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| Open AccessTransition between protein-like and polymer-like dynamic behavior: Internal friction in unfolded apomyoglobin depends on denaturing conditions
- Livia Balacescu
- , Tobias E. Schrader
- & Andreas M. Stadler
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| Open AccessCo-existence of PrPD types 1 and 2 in sporadic Creutzfeldt-Jakob disease of the VV subgroup: phenotypic and prion protein characteristics
- Ignazio Cali
- , Gianfranco Puoti
- & Pierluigi Gambetti
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Article
| Open AccessAnalysis of the co-translational assembly of the fungal fatty acid synthase (FAS)
- Manuel Fischer
- , Mirko Joppe
- & Martin Grininger
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| Open AccessLiquid-like droplet formation by tumor suppressor p53 induced by multivalent electrostatic interactions between two disordered domains
- Kiyoto Kamagata
- , Saori Kanbayashi
- & Satoshi Takahashi
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| Open AccessThe novel missense mutation Met48Lys in FKBP22 changes its structure and functions
- Yoshihiro Ishikawa
- , Nobuyo Mizuno
- & Hans Peter Bächinger
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| Open AccessThe N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
- Matteo Runfola
- , Alfonso De Simone
- & Giuliana Fusco