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| Open AccessAcute-phase serum amyloid A for early detection of hepatocellular carcinoma in cirrhotic patients with low AFP level
- Jin-Lin Wu
- , Tung-Hung Su
- & Yun-Ru Chen
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| Open AccessRational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons
- Alessandro Soloperto
- , Deborah Quaglio
- & Alberto Boffi
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| Open AccessThioredoxin interacting protein protects mice from fasting induced liver steatosis by activating ER stress and its downstream signaling pathways
- Hiroyuki Miyahara
- , Kosei Hasegawa
- & Hirokazu Tsukahara
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| Open AccessProteomic analysis of heat-stable proteins revealed an increased proportion of proteins with compositionally biased regions
- Hongsun Park
- , Tomoyuki Yamanaka
- & Nobuyuki Nukina
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| Open AccessElectric-field induced modulation of amorphous protein aggregates: polarization, deformation, and reorientation
- Kyongok Kang
- & Florian Platten
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| Open AccessA human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer’s disease
- Elena Ficulle
- , Sarubini Kananathan
- & Suchira Bose
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| Open AccessA small molecule high throughput screening platform to profile conformational properties of nascent, ribosome-bound proteins
- Hideki Shishido
- , Jae Seok Yoon
- & William R. Skach
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| Open AccessInvestigating binding dynamics of trans resveratrol to HSA for an efficient displacement of aflatoxin B1 using spectroscopy and molecular simulation
- Mohd Aamir Qureshi
- & Saleem Javed
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| Open AccessComprehensive characterization and molecular insights into the salt tolerance of a Cu, Zn-superoxide dismutase from an Indian Mangrove, Avicennia marina
- Rajat Kanti Sarkar
- , Moumita Bhowmik
- & Kashinath Bhattacharya
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| Open AccessAluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy
- Matthew John Mold
- & Christopher Exley
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| Open AccessRational design of a helical peptide inhibitor targeting c-Myb–KIX interaction
- Shunji Suetaka
- , Yoshiki Oka
- & Munehito Arai
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| Open AccessThe N-terminal tail of the hydrophobin SC16 is not required for rodlet formation
- Kathleen L. Vergunst
- & David N. Langelaan
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| Open AccessPeptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development
- Thyago R. Cardim-Pires
- , Ricardo Sant’Anna
- & Debora Foguel
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| Open AccessHoney bee sHSP are responsive to diverse proteostatic stresses and potentially promising biomarkers of honey bee stress
- Samantha R. Shih
- , Dunay M. Bach
- & Jonathan W. Snow
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| Open AccessCa2+ imbalance caused by ERdj5 deletion affects mitochondrial fragmentation
- Riyuji Yamashita
- , Shohei Fujii
- & Kazuhiro Nagata
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| Open AccessNematode CDC-37 and DNJ-13 form complexes and can interact with HSP-90
- Lukas Schmauder
- , Eva Absmeier
- & Klaus Richter
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| Open AccessProteomic and molecular dynamic investigations of PTM-induced structural fluctuations in breast and ovarian cancer
- Dmitry Tikhonov
- , Liudmila Kulikova
- & Anna L. Kaysheva
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| Open AccessControl of membrane protein homeostasis by a chaperone-like glial cell adhesion molecule at multiple subcellular locations
- Haijin Xu
- , Sandra Isenmann
- & Pirjo M. Apaja
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| Open AccessNovel cryo-EM structure of an ADP-bound GroEL–GroES complex
- Sofia S. Kudryavtseva
- , Evgeny B. Pichkur
- & Tatiana B. Stanishneva-Konovalova
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| Open AccessProtein disulphide isomerase (PDI) is protective against amyotrophic lateral sclerosis (ALS)-related mutant Fused in Sarcoma (FUS) in in vitro models
- S. Parakh
- , E. R. Perri
- & J. D. Atkin
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| Open AccessThe chaperone HSPB1 prepares protein aggregates for resolubilization by HSP70
- Conrado C. Gonçalves
- , Itai Sharon
- & Jason C. Young
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| Open AccessEquine pituitary pars intermedia dysfunction: a spontaneous model of synucleinopathy
- Jessica S. Fortin
- , Ashley A. Hetak
- & Harold C. Schott II
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| Open AccessExogenous misfolded protein oligomers can cross the intestinal barrier and cause a disease phenotype in C. elegans
- Michele Perni
- , Benedetta Mannini
- & Michele Vendruscolo
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| Open AccessAnthrax toxin translocation complex reveals insight into the lethal factor unfolding and refolding mechanism
- Alexandra J. Machen
- , Mark T. Fisher
- & Bret D. Freudenthal
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| Open AccessIpomoeassin-F disrupts multiple aspects of secretory protein biogenesis
- Peristera Roboti
- , Sarah O’Keefe
- & Stephen High
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| Open AccessAn evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β
- Devkee M. Vadukul
- , Céline Vrancx
- & Pascal Kienlen-Campard
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| Open AccessProtein model accuracy estimation empowered by deep learning and inter-residue distance prediction in CASP14
- Xiao Chen
- , Jian Liu
- & Jianlin Cheng
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| Open AccessNon-coding RNA suppresses FUS aggregation caused by mechanistic shear stress on pipetting in a sequence-dependent manner
- Nesreen Hamad
- , Ryoma Yoneda
- & Masato Katahira
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| Open AccessThe heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction
- Casandra Gomez-Paredes
- , Michael A. Mason
- & Gillian P. Bates
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| Open AccessAn efficient alpha helix model and simulation framework for stationary electrostatic interaction force estimation
- Guy G. Butcher
- , William S. Harwin
- & Chris I. Jones
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| Open AccessC subunit of the ATP synthase is an amyloidogenic calcium dependent channel-forming peptide with possible implications in mitochondrial permeability transition
- Giuseppe Federico Amodeo
- , Brenda Yasie Lee
- & Evgeny V. Pavlov
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| Open AccessDeciphering molecular details of the RAC–ribosome interaction by EPR spectroscopy
- Sandra J. Fries
- , Theresa S. Braun
- & Elke Deuerling
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| Open AccessPolyQ-expanded proteins impair cellular proteostasis of ataxin-3 through sequestering the co-chaperone HSJ1 into aggregates
- Hong-Wei Yue
- , Jun-Ye Hong
- & Hong-Yu Hu
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| Open AccessIdentification of critical amino acid residues in the regulatory N-terminal domain of PMEL
- Susan M. Mitchell
- , Morven Graham
- & Ralf M. Leonhardt
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| Open AccessDegradation of insulin amyloid by antibiotic minocycline and formation of toxic intermediates
- Wakako Mori
- , Keisuke Yuzu
- & Tamotsu Zako
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| Open AccessStability of uniformly labeled (13C and 15N) cytochrome c and its L94G mutant
- Abdullah Naiyer
- , Bushra Khan
- & Faizan Ahmad
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| Open AccessShear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels
- Zenon Toprakcioglu
- & Tuomas P. J. Knowles
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| Open AccessCrystal structure of P. falciparum Cpn60 bound to ATP reveals an open dynamic conformation before substrate binding
- Brian Nguyen
- , Rui Ma
- & Niraj H. Tolia
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| Open AccessSingular and short-term anesthesia exposure in the developing brain induces persistent neuronal changes consistent with chronic neurodegenerative disease
- Kaley Hogarth
- , Ramesh Babu Vanama
- & Jason T. Maynes
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| Open AccessThe less conserved metal-binding site in human CRISP1 remains sensitive to zinc ions to permit protein oligomerization
- Jie Sheng
- , Bart M. Gadella
- & J. Bernd Helms
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| Open AccessPharmacological targeting of host chaperones protects from pertussis toxin in vitro and in vivo
- Katharina Ernst
- , Ann-Katrin Mittler
- & Holger Barth
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| Open AccessSensitive protein misfolding cyclic amplification of sporadic Creutzfeldt–Jakob disease prions is strongly seed and substrate dependent
- Maxime Bélondrade
- , Simon Nicot
- & Daisy Bougard
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| Open AccessExercise alters the mitochondrial proteostasis and induces the mitonuclear imbalance and UPRmt in the hypothalamus of mice
- Renata R. Braga
- , Barbara M. Crisol
- & Eduardo R. Ropelle
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| Open AccessClinically-identified C-terminal mutations in fibulin-3 are prone to misfolding and destabilization
- DaNae R. Woodard
- , Emi Nakahara
- & John D. Hulleman
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| Open AccessThe G127V variant of the prion protein interferes with dimer formation in vitro but not in cellulo
- Sudheer Babu Sangeetham
- , Anna Dorothee Engelke
- & Ervin Welker
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| Open AccessTethering-induced destabilization and ATP-binding for tandem RRM domains of ALS-causing TDP-43 and hnRNPA1
- Mei Dang
- , Yifan Li
- & Jianxing Song
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| Open AccessElucidating the regulatory mechanism of Swi1 prion in global transcription and stress responses
- Zhiqiang Du
- , Jeniece Regan
- & Liming Li
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| Open AccessFunctionalization of amyloid fibrils via the Bri2 BRICHOS domain
- Henrik Biverstål
- , Rakesh Kumar
- & Jan Johansson
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| Open AccessThe change of conditions does not affect Ros87 downhill folding mechanism
- Rinaldo Grazioso
- , Sara García-Viñuales
- & Gaetano Malgieri