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Evidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6
- James M. Gruschus
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Transcriptional analysis reveals that the intracellular lipid accumulation impairs gene expression profiles involved in insulin response-associated cardiac functionality
- Virginia Actis Dato
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STAT3 suppression and β-cell ablation enhance α-to-β reprogramming mediated by Pdx1
- Yuka Wakabayashi
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Insulin sensitivity is associated with the observed variation of de novo lipid synthesis and body composition in finishing pigs
- Hector Hernando Salgado
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Membrane extraction with styrene-maleic acid copolymer results in insulin receptor autophosphorylation in the absence of ligand
- Kerrie A. Morrison
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Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase
- Katarzyna Figlak
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The promise(s) of mesenchymal stem cell therapy in averting preclinical diabetes: lessons from in vivo and in vitro model systems
- Nagasuryaprasad Kotikalapudi
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Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma
- Sophie Jacques
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- & Souad Rahmouni
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Domeless receptor loss in fat body tissue reverts insulin resistance induced by a high-sugar diet in Drosophila melanogaster
- Fernanda Lourido
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Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1
- Benoit Denhez
- , Marina Rousseau
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Insulin activates hepatic Wnt/β-catenin signaling through stearoyl-CoA desaturase 1 and Porcupine
- Régine Cabrae
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Resveratrol alleviates obesity-induced skeletal muscle inflammation via decreasing M1 macrophage polarization and increasing the regulatory T cell population
- Maryam Shabani
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Increased mitochondrial and lipid metabolism is a conserved effect of Insulin/PI3K pathway downregulation in adipose tissue
- Lucia Bettedi
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Expression and functional analysis of the hydrogen peroxide biosensors HyPer and HyPer2 in C2C12 myoblasts/myotubes and single skeletal muscle fibres
- Escarlata Fernández-Puente
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The role of a new insulin-like peptide in the pearl oyster Pinctada fucata martensii
- Hua Zhang
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Neurotropic and modulatory effects of insulin-like growth factor II in Aplysia
- Nikolay Vadimovich Kukushkin
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Adipose cell size changes are associated with a drastic actin remodeling
- Björn Hansson
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Statins exacerbate glucose intolerance and hyperglycemia in a high sucrose fed rodent model
- Sriram Seshadri
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Insulin-dependent GLUT4 trafficking is not regulated by protein SUMOylation in L6 myocytes
- Ruth E. Carmichael
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The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
- Alessio Reggio
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Cytohesin-3 is required for full insulin receptor signaling and controls body weight via lipid excretion
- Bettina Jux
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Anti-adipogenic effects of KD025 (SLx-2119), a ROCK2-specific inhibitor, in 3T3-L1 cells
- Duy Trong Vien Diep
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Inhibition of C1-Ten PTPase activity reduces insulin resistance through IRS-1 and AMPK pathways
- Heeyoon Jeong
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CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity
- Christian Borgo
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Hydrogen Sulphide Treatment Increases Insulin Sensitivity and Improves Oxidant Metabolism through the CaMKKbeta-AMPK Pathway in PA-Induced IR C2C12 Cells
- Xubo Chen
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Effects of Lipoic Acid on High-Fat Diet-Induced Alteration of Synaptic Plasticity and Brain Glucose Metabolism: A PET/CT and 13C-NMR Study
- Zhigang Liu
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Role of insulin receptor substrates in the progression of hepatocellular carcinoma
- Yoshitaka Sakurai
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Development of a Whole Organism Platform for Phenotype-Based Analysis of IGF1R-PI3K-Akt-Tor Action
- Chengdong Liu
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Hepatic MiR-291b-3p Mediated Glucose Metabolism by Directly Targeting p65 to Upregulate PTEN Expression
- Jun Guo
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PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639
- Hae-In Song
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11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) mediates insulin resistance through JNK activation in adipocytes
- Kesong Peng
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LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL)
- Gang Chen
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A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes
- TingYu Liu
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Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus
- Yuehui Zhang
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Thioredoxin reductase 1 suppresses adipocyte differentiation and insulin responsiveness
- Xiaoxiao Peng
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Dexras1 links glucocorticoids to insulin-like growth factor-1 signaling in adipogenesis
- Hyo Jung Kim
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Regulating the effects of GPR21, a novel target for type 2 diabetes
- Siobhán Leonard
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- & John B. C. Findlay
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PfIRR Interacts with HrIGF-I and Activates the MAP-kinase and PI3-kinase Signaling Pathways to Regulate Glycogen Metabolism in Pinctada fucata
- Yu Shi
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Resveratrol induces autophagy by directly inhibiting mTOR through ATP competition
- Dohyun Park
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Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance
- Xiulan Chen
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Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production
- Matthijs P. Groeneveld
- , Gemma V. Brierley
- & Robert K. Semple
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Nutritional conditions regulate transcriptional activity of SF-1 by controlling sumoylation and ubiquitination
- Jiwon Lee
- , Dong Joo Yang
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Direct Evidence that Myocardial Insulin Resistance following Myocardial Ischemia Contributes to Post-Ischemic Heart Failure
- Feng Fu
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- & Feng Gao
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An optogenetic system for interrogating the temporal dynamics of Akt
- Yoshihiro Katsura
- , Hiroyuki Kubota
- & Takeaki Ozawa
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DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression
- Mohamed Abu-Farha
- , Preethi Cherian
- & Jehad Abubaker
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GADD34-deficient mice develop obesity, nonalcoholic fatty liver disease, hepatic carcinoma and insulin resistance
- Naomi Nishio
- & Ken-ichi Isobe
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Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway
- Xukai Wang
- , Gang He
- & Bo Zhang
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Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth
- Michiko Shigyo
- , Tomoharu Kuboyama
- & Chihiro Tohda
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Sestrin2 inhibits mTORC1 through modulation of GATOR complexes
- Jeong Sig Kim
- , Seung-Hyun Ro
- & Jun Hee Lee
STAP-2 facilitates insulin signaling through binding to CAP/c-Cbl and regulates adipocyte differentiation