Synaesthetes who experience colours when perceiving or representing numbers exhibit structural and functional differences in cortical areas that are involved in number and colour processing compared to non-synaesthetes. Using transcranial magnetic stimulation or transcranial direct current stimulation, the authors showed that in humans, grapheme-colour synaesthesia is characterized by enhanced cortical excitability in the primary visual cortex and can be augmented or attenuated with cathodal or anodal stimulation, respectively.
ORIGINAL RESEARCH PAPER
Terhune, D. B. et al. Enhanced cortical excitability in grapheme-color synesthesia and its modulation. Curr. Biol. 21, 2006–2009 (2011)Article
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Flight, M. Excitability modulates synaesthesia. Nat Rev Neurosci 13, 2 (2012). https://doi.org/10.1038/nrn3159
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DOI: https://doi.org/10.1038/nrn3159