Jennie Vallis

Read the December issue

Including articles on remyelination, the axonal cytoskeleton, the origins of schizophrenia and the role of the dopamine motive system in addiction and obesity.

Latest Reviews

  • Review |

    Promoting remyelination may be an effective therapeutic strategy for various disorders that are characterized by a loss of myelin, including multiple sclerosis. In this Review, Franklin and ffrench-Constant discuss recent developments in our understanding of remyelination and the efforts that are underway to enhance this process.

    • Robin J. M. Franklin
    •  & Charles ffrench-Constant
  • Review |

    The dopamine motive system, which integrates reinforcement and motivation, is influenced by obesogenic foods and addictive drugs. In this Review, Volkow and colleagues highlight how these stimuli sensitize the subject's motivation towards them while desensitizing the subject's motivation towards alternative reinforcers.

    • Nora D. Volkow
    • , Roy A. Wise
    •  & Ruben Baler
  • Review |

    An axon's function is dictated by its morphology and, thus, by the properties and organization of the axonal cytoskeleton. Leterrier et al. describe how advances in super-resolution and live-cell imaging are transforming our understanding of the molecular architecture of the axonal shaft.

    • Christophe Leterrier
    • , Pankaj Dubey
    •  & Subhojit Roy
  • Review |

    A causal explanation for the pathogenesis of schizophrenia is lacking. In this Review, Birnbaum and Weinberger explore recent genetic studies of schizophrenia and discuss how genetic and epigenetic risk of the disorder may converge to perturb key neurodevelopmental trajectories.

    • Rebecca Birnbaum
    •  & Daniel R. Weinberger
  • Review |

    Only primates possess 'cytoarchitectonic area 10' in anterior prefrontal cortex, and its function is unknown. In this Review, Mansouri and colleagues argue that area 10 monitors the relative importance of current and alternative goals.

    • Farshad Alizadeh Mansouri
    • , Etienne Koechlin
    • , Marcello G. P. Rosa
    •  & Mark J. Buckley
  • Review |

    Individuals with autism show differences in both social cognition and basic sensory processing. In this Review, Robertson and Baron-Cohen discuss human and animal studies of sensory processing in autism and present possible explanations of how they relate to changes in neural processing and cognition.

    • Caroline E. Robertson
    •  & Simon Baron-Cohen

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