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Opinion
Blebs lead the way: how to migrate without lamellipodia
Guillaume Charras & Ewa Paluch
Published online: 16 July 2008 | doi:10.1038/nrm2453
Membrane blebs are considered to be a hallmark of apoptosis; however, blebs are also observed in healthy cells during cytokinesis and cell motility. What are the potential mechanisms by which blebbing can be polarized and translated into movement? And what are the advantages of blebbing motility?
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Until print versions of AOP papers are published, they should be cited in the style "Nature Reviews Molecular Cell Biology AOP, published online day month year; doi:10.1038/nrmXXX". Once the print version (identical to the AOP) is published, it should be cited as follows: "Nature Reviews Molecular Cell Biology volume number, page range (year); doi:10.1038/nrmXXX".