A small-bowel biopsy is currently required in the diagnosis of celiac disease in children. The European Society for Pediatric Gastroenterology, Hepatology and Nutrition has now presented new guidelines for the diagnosis of celiac disease, which indicate that small-bowel biopsy could be avoided in certain cases.
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References
Di Sabatino, A. & Corazza, G. R. Coeliac disease. Lancet 373, 1480–1493 (2009).
Zawahir, S., Safta, A. & Fasano, A. Pediatric celiac disease. Curr. Opin. Pediatr. 21, 655–660 (2009).
Mustalahti, K. et al. The prevalence of celiac disease in Europe: Results of a centralized, international mass screening project. Ann. Med. 42, 587–595 (2010).
Myléus, A. et al. Celiac disease revealed in 3% of Swedish 12-year-olds born during an epidemic. J. Pediatr. Gastroenterol. Nutr. 49, 170–176 (2009).
Husby, S. et al. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease. J. Pediatr. Gastroenterol. Nutr. 54, 136–160 (2012).
Meeuwisse, G. W. Diagnostic criteria in coeliac disease. Acta Paediatr. Scand. 59, 461–463 (1970).
[No authors listed]. Revised criteria for diagnosis of coeliac disease. Report of Working Group of European Society of Paediatric Gastroenterology and Nutrition. Arch. Dis. Child. 65, 909–911 (1990).
Wolters, V. M. et al. Is gluten challenge really necessary for the diagnosis of coeliac disease in children younger than age 2 years? J. Pediatr. Gastroenterol. Nutr. 48, 566–579 (2009).
Högberg, L. & Stenhammar, L. Celiac disease. Diagnosis criteria in young children. Nat. Rev. Gastroenterol. Hepatol. 6, 447–448 (2009).
Ivarsson, A., Högberg, L. & Stenhammar, L. The Swedish Childhood Coeliac Disease Working Group after 20 years: history and future. Acta Paediatr. 99, 1429–1431 (2010).
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Högberg, L., Stenhammar, L. Pediatric celiac disease—is a diagnostic biopsy necessary?. Nat Rev Gastroenterol Hepatol 9, 127–128 (2012). https://doi.org/10.1038/nrgastro.2012.11
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DOI: https://doi.org/10.1038/nrgastro.2012.11
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