Coeliac disease is an autoimmune disorder of the small intestine caused by immune cells reacting to ingested gluten present in wheat, rye and barley and also to small bowel tissue. It occurs in genetically predisposed individuals, starting in childhood, and can result in the loss of microvilli structure, failed intestinal absorption and malnutrition.
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Research Highlights |Nature Reviews Gastroenterology and Hepatology 13, 314–315