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Pathology

Does nodal micrometastasis impact outcome in biliary cancer?

Microscopic deposits of tumor cells in regional lymph nodes can be detected using immunohistochemical techniques in patients without conventional histopathological evidence of lymph-node involvement. In the case of bile duct cancer, these micrometastases have an intermediate prognostic significance between that of positive and negative conventional pathology.

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Correspondence to Peter J. Friend.

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Silva, M., Friend, P. Does nodal micrometastasis impact outcome in biliary cancer?. Nat Rev Clin Oncol 7, 680–681 (2010). https://doi.org/10.1038/nrclinonc.2010.184

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