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Decade in review—valvular disease

Current perspectives on treatment of valvular heart disease

Tremendous advances in the understanding and treatment of structural heart valve disease have been made in the past decade, including widespread utilization of minimally-invasive surgical procedures and the invention and evolution of numerous interventional techniques. These innovations will become the norm in therapy for valvular disease in the future.

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Figure 1: Development of isolated AVR in Germany from 1994 to 2013.

References

  1. Bavaria, J. E. et al. The St Jude Medical Trifecta aortic pericardial valve: results from a global, multicenter, prospective clinical study. J. Thorac. Cardiovasc. Surg. 147, 590–597 (2014).

    Article  Google Scholar 

  2. Cribier, A. et al. Percutaneous transcatheter implantation of an aortic valve prosthesis for calcific aortic stenosis: first human case description. Circulation 106, 3006–3008 (2002).

    Article  Google Scholar 

  3. Acker, M. A. et al. Mitral-valve repair versus replacement for severe ischemic mitral regurgitation. N. Engl. J. Med. 370, 23–32 (2014).

    Article  CAS  Google Scholar 

  4. Glower, D. D. et al. Percutaneous mitral valve repair for mitral regurgitation in high-risk patients: results of the EVEREST II study. J. Am. Coll. Cardiol. 64, 172–181 (2014).

    Article  Google Scholar 

  5. Navia, J. L. et al. Moderate tricuspid regurgitation with left-sided degenerative heart valve disease: to repair or not to repair? Ann. Thorac. Surg. 93, 59–67 (2012).

    Article  Google Scholar 

  6. Dvir, D. et al. Transcatheter aortic valve implantation in failed bioprosthetic surgical valves. JAMA 312, 162–170 (2014).

    Article  CAS  Google Scholar 

  7. Momenah, T. S. et al. Extended application of percutaneous pulmonary valve implantation. J. Am. Coll. Cardiol. 53, 1859–1863 (2009).

    Article  Google Scholar 

  8. Smith, C. R. et al. Transcatheter versus surgical aortic-valve replacement in high-risk patients. N. Engl. J. Med. 364, 2187–2198 (2011).

    Article  CAS  Google Scholar 

  9. Adams, D. H. et al. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N. Engl. J. Med. 370, 1790–1798 (2014).

    Article  CAS  Google Scholar 

  10. Mohr, F. W. et al. The German Aortic Valve Registry: 1-year results from 13 680 patients with aortic valve disease. Eur. J. Cardiothorac. Surg. http://dx.doi.org/10.1093/ejcts/ezu290.

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Correspondence to Friedrich W. Mohr.

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The author declares no competing financial interests.

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Mohr, F. Current perspectives on treatment of valvular heart disease. Nat Rev Cardiol 11, 637–638 (2014). https://doi.org/10.1038/nrcardio.2014.138

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