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Implanted materials

Larger is stealthier

Implanted spheres with a diameter larger than 1.5 mm escape fibrotic responses, thereby extending the survival time of the encapsulated therapeutic cells.

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Figure 1: Foreign body response to alginate spheres encapsulating insulin-producing islet cells.

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Correspondence to Ruud A. Bank.

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Bank, R. Larger is stealthier. Nature Mater 14, 558–559 (2015). https://doi.org/10.1038/nmat4304

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