Implanted spheres with a diameter larger than 1.5 mm escape fibrotic responses, thereby extending the survival time of the encapsulated therapeutic cells.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Anderson, J. M. & McNalley, A. K. Semin. Immunopathol. 33, 221–233 (2011).
Londono, R. & Badylak, S. F. Ann. Biomed. Eng. 43, 577–592 (2014).
Veiseh, O. et al. Nature Mater. 14, 643–651 (2015).
Burnett, S. H. et al. J. Leukoc. Biol. 75, 612–623 (2004).
Duffield, J. S. et al. Annu. Rev. Pathol. Mech. Dis. 8, 241–276 (2013).
Lichtnekert, J. et al. Curr. Opin. Pharmacol. 13, 555–564 (2013).
Scharp, D. W. & Marchetti, P. Adv. Drug Del. Rev. 67–68, 35–73 (2014).
Wynn, T. A. & Ramalingam, T. R. Nature Med. 18, 1028–1040 (2012).
Dang, T. T. et al. Biomaterials 32, 4464–4470 (2011).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bank, R. Larger is stealthier. Nature Mater 14, 558–559 (2015). https://doi.org/10.1038/nmat4304
Published:
Issue Date:
DOI: https://doi.org/10.1038/nmat4304