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This latest installment in a series of commentaries examining funding issue in biomedical research,focuses on the role of the Medical research Council(MRC)—the largest funding agency in the United Kingdom. George Radda, Chief Executive of the MRC, describes how funding decisions are made and priorities identified and considers future developement for the MRC.
New evidence suggests that the cystic fibrosis transmembrane conductance regulator acts as a specific receptor and clearance mechanism for Pseudomonas aeruginosa.
The differential expression and signaling abilities of HIV-1 co-receptors may explain why macrophage-tropic strains of the virus are prefentially transmitted (pages 1369–1375).
Antibodies against human herpesvirus-6 have been found in patients with multiple sclerosis. Could this be another sighting in the hunt for the viral trigger of the disease (pages 1394–1397)?
Locally growing malignant brain tumors provide a reasonable starting point for developing targeted strategies of anti-cancer therapy (pages 1354–1368).
