Several physiological and pathological events taking place postnatally in or around the pancreatic islets of Langerhans have been implicated in the initiation of type 1 diabetes. A new study highlights the contribution of neutrophils and how they, together with B1a cells and plasmacytoid dendritic cells (pDCs), may start the autoimmune process (pages 65–73).
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Creusot, R. Initiating type I diabetes: new suspects in the lineup. Nat Med 19, 18–20 (2013). https://doi.org/10.1038/nm.3044
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DOI: https://doi.org/10.1038/nm.3044