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| Five specially commissioned articles analyze the influence of the innate immune system on adaptive immunity. This focus is available free to registrants during the month of October. |
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| Editorial | Top |
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Focus on Bridging Innate and Adaptive Immunity
Toll Bridges p969
doi:10.1038/ni1004-969
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(54K)
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| Overview | Top |
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Focus on Bridging Innate and Adaptive Immunity
The interface between innate and adaptive immunity pp971 - 974
Kasper Hoebe, Edith Janssen
& Bruce Beutler
doi:10.1038/ni1004-971
Abstract | Full text | PDF
(396K)
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| Perspective | Top |
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Focus on Bridging Innate and Adaptive Immunity
Toll-like receptors in the pathogenesis of human disease pp975 - 979
Donald N Cook, David S Pisetsky
& David A Schwartz
Published online: 28 September 2004 | doi:10.1038/ni1116
Abstract | Full text | PDF
(392K)
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| Reviews | Top |
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Focus on Bridging Innate and Adaptive Immunity
The complement system in regulation of adaptive immunity pp981 - 986
Michael C Carroll
Published online: 28 September 2004 | doi:10.1038/ni1113
Abstract | Full text | PDF
(231K)
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Focus on Bridging Innate and Adaptive Immunity
Toll-like receptor control of the adaptive immune responses pp987 - 995
Akiko Iwasaki
& Ruslan Medzhitov
Published online: 28 September 2004 | doi:10.1038/ni1112
Abstract | Full text | PDF
(840K)
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Focus on Bridging Innate and Adaptive Immunity
Interplay of natural killer cells and their receptors with the adaptive immune response pp996 - 1002
David H Raulet
Published online: 28 September 2004 | doi:10.1038/ni1114
Abstract | Full text | PDF
(1,195K)
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| Research Highlights | Top |
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Focus on Bridging Innate and Adaptive Immunity
Research Highlights p1003
doi:10.1038/ni1004-1003
Full text | PDF
(64K)
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| Correspondence | Top |
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Cultures and identities p1005
Arthur M Silverstein
doi:10.1038/ni1004-1005
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(53K)
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| News and Views | Top |
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RAPL: taking the Rap in immunity pp1007 - 1008
Leo S Price
& Johannes L Bos
doi:10.1038/ni1004-1007
Abstract | Full text | PDF
(148K)
See also: Article by Katagiri et al. |
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Unmasking connections in transmembrane immune signaling pp1008 - 1010
Jamey D Marth
doi:10.1038/ni1004-1008
Abstract | Full text | PDF
(255K)
See also: Article by Poe et al. |
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DUBbing down innate immunity pp1010 - 1012
Neal Silverman
& Katherine Fitzgerald
doi:10.1038/ni1004-1010
Abstract | Full text | PDF
(306K)
See also: Article by Boone et al. |
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A polarizing situation pp1012 - 1013
Tasha N Sims
& Michael L Dustin
doi:10.1038/ni1004-1012
Abstract | Full text | PDF
(450K)
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Research Highlights p1015
doi:10.1038/ni1004-1015
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(61K)
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| Articles | Top |
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Long-range intrachromosomal interactions in the T helper type 2 cytokine locus pp1017 - 1027
Charalampos G Spilianakis
& Richard A Flavell
Published online: 19 September 2004 | doi:10.1038/ni1115
Abstract | Full text | PDF
(973K)
| Supplementary Information |
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Recessive tolerance to preproinsulin 2 reduces but does not abolish type 1 diabetes pp1028 - 1035
Elmar Jaeckel, Myra A Lipes
& Harald von Boehmer
Published online: 19 September 2004 | doi:10.1038/ni1120
Abstract | Full text | PDF
(460K)
| Supplementary Information |
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GA binding protein regulates interleukin 7 receptor  -chain gene expression in T cells pp1036 - 1044
Hai-Hui Xue, Julie Bollenbacher, Valentina Rovella, Radhika Tripuraneni, Yu-Bin Du, Cheng-Yu Liu, Ann Williams, J Philip McCoy
& Warren J Leonard
Published online: 07 September 2004 | doi:10.1038/ni1117
Abstract | Full text | PDF
(713K)
| Supplementary Information |
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Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking pp1045 - 1051
Koko Katagiri, Noriko Ohnishi, Kenji Kabashima, Tomonori Iyoda, Naoki Takeda, Yoichi Shinkai, Kayo Inaba
& Tatsuo Kinashi
Published online: 07 September 2004 | doi:10.1038/ni1111
Abstract | Full text | PDF
(400K)
| Supplementary Information
See also: News and Views by Price & Bos |
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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses pp1052 - 1060
David L Boone, Emre E Turer, Eric G Lee, Regina-Celeste Ahmad, Matthew T Wheeler, Colleen Tsui, Paula Hurley, Marcia Chien, Sophia Chai, Osamu Hitotsumatsu, Elizabeth McNally, Cecile Pickart
& Averil Ma
Published online: 29 August 2004 | doi:10.1038/ni1110
Abstract | Full text | PDF
(723K)
See also: News and Views by Silverman & Fitzgerald |
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Interferon- induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 pp1061 - 1068
Taro Kawai, Shintaro Sato, Ken J Ishii, Cevayir Coban, Hiroaki Hemmi, Masahiro Yamamoto, Kenta Terai, Michiyuki Matsuda, Jun-ichiro Inoue, Satoshi Uematsu, Osamu Takeuchi
& Shizuo Akira
Published online: 07 September 2004 | doi:10.1038/ni1118
Abstract | Full text | PDF
(328K)
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Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription pp1069 - 1077
Holly Maier, Rachel Ostraat, Hua Gao, Scott Fields, Susan A Shinton, Kay L Medina, Tomokatsu Ikawa, Cornelis Murre, Harinder Singh, Richard R Hardy
& James Hagman
Published online: 12 September 2004 | doi:10.1038/ni1119
Abstract | Full text | PDF
(562K)
| Supplementary Information |
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CD22 regulates B lymphocyte function in vivo through both ligand-dependent and ligand-independent mechanisms pp1078 - 1087
Jonathan C Poe, Yoko Fujimoto, Minoru Hasegawa, Karen M Haas, Ann S Miller, Isaac G Sanford, Cheryl B Bock, Manabu Fujimoto
& Thomas F Tedder
Published online: 19 September 2004 | doi:10.1038/ni1121
Abstract | Full text | PDF
(1,202K)
| Supplementary Information
See also: News and Views by Marth |
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