The mutator activation-induced cytidine deaminase is essential for immunoglobulin diversification but can be detrimental in other settings. A new comprehensive analysis investigates how its gene expression is regulated.
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Lee-Theilen, M., Chaudhuri, J. Walking the AID tightrope. Nat Immunol 11, 107–109 (2010). https://doi.org/10.1038/ni0210-107
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DOI: https://doi.org/10.1038/ni0210-107