Genetic homogeneity of Icelanders: fact or fiction?pp373 - 374 Einar Árnason, Hlynur Sigurgíslason
& Eiríkur Benedikz doi:10.1038/78036 Full text|PDF
(74K)
Hot-stop PCR: a simple and general assay for linear quantitation of allele ratiospp375 - 376 Hiroshi Uejima, Maxwell P. Lee, Hengmi Cui
& Andrew P. Feinberg doi:10.1038/78040 Abstract|Full text|PDF
(300K)
The NOTCH4 locus is associated with susceptibility to schizophrenia
pp376 - 377 Jun Wei
& Gwynneth P. Hemmings doi:10.1038/78044 Abstract|Full text|PDF
(170K)
The roads from phenotypic variation to gene discovery: mutagenesis versus QTLspp381 - 384 Joseph H. Nadeau
& Wayne N. Frankel doi:10.1038/78051 Abstract|Full text|PDF
(109K)
Amino-terminal fragments of mutant huntingtin show selective accumulation
in striatal neurons and synaptic toxicitypp385 - 389 He Li, Shi-Hua Li, Heather Johnston, Peggy F. Shelbourne
& Xiao-Jiang Li doi:10.1038/78054 Abstract|Full text|PDF
(891K)
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Mesp2 initiates somite segmentation through the Notch signalling pathway
pp390 - 396 Yu Takahashi, Ken-ichi Koizumi, Atsuya Takagi, Satoshi Kitajima, Tohru Inoue, Haruhiko Koseki
& Yumiko Saga doi:10.1038/78062 Abstract|Full text|PDF
(1,131K)
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Human microphthalmia associated with mutations in the retinal homeobox gene CHX10pp397 - 401 E. Ferda Percin, Lynda A. Ploder, Jessica J. Yu, Kemal Arici, D. Jonathan Horsford, Adam Rutherford, Bharati Bapat, Diane W. Cox, Alessandra M.V. Duncan, Vitauts I. Kalnins, Aysegul Kocak-Altintas, Jane C. Sowden, Elias Traboulsi, Mansoor Sarfarazi
& Roderick R. McInnes doi:10.1038/78071 Abstract|Full text|PDF
(608K)
|Supplementary Information
Neurofibrillary tangles, amyotrophy and progressive motor disturbance
in mice expressing mutant (P301L) tau proteinpp402 - 405 Jada Lewis, Eileen McGowan, Julia Rockwood, Heather Melrose, Parimala Nacharaju, Marjon Van Slegtenhorst, Katrina Gwinn-Hardy, M. P Murphy, Matt Baker, Xin Yu, Karen Duff, John Hardy, Anthony Corral, Wen-Lang Lin, Shu-Hui Yen, Dennis W. Dickson, Peter Davies
& Mike Hutton doi:10.1038/78078 Abstract|Full text|PDF
(703K)
EIF2AK3, encoding translation initiation factor 2- kinase 3, is mutated in patients with Wolcott-Rallison syndromepp406 - 409 Marc Delépine, Marc Nicolino, Timothy Barrett, Mahamadee Golamaully, G. Mark Lathrop
& Cécile Julier doi:10.1038/78085 Abstract|Full text|PDF
(210K)
|Supplementary Information
Adaptive evolution of the tumour suppressor BRCA1 in humans and chimpanzeespp410 - 413 Gavin A. Huttley, Simon Easteal, Melissa C. Southey, Andrea Tesoriero, Graham G. Giles, Margaret R.E. McCredie, John L. Hopper
& Deon J. Venter doi:10.1038/78092 Abstract|Full text|PDF
(100K)
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalkpp414 - 418 Michael M. Halford, Jane Armes, Michael Buchert, Virginia Meskenaite, Dianne Grail, Margaret L. Hibbs, Andrew F. Wilks, Peter G. Farlie, Don F. Newgreen, Christopher M. Hovens
& Steven A. Stacker doi:10.1038/78099 Abstract|Full text|PDF
(809K)
Recessive Robinow syndrome, allelic to dominant brachydactyly type B, is caused by mutation of ROR2pp419 - 422 Ali R. Afzal, Anna Rajab, Christiane D. Fenske, Michael Oldridge, Navaratnam Elanko, Eliana Ternes-Pereira, Beyhan Tüysüz, Victoria A. Murday, Michael A. Patton, Andrew O.M. Wilkie
& Steve Jeffery doi:10.1038/78107 Abstract|Full text|PDF
(457K)
Mutation of the gene encoding the ROR2 tyrosine kinase causes autosomal recessive Robinow syndromepp423 - 426 Hans van Bokhoven, Jacopo Celli, Hülya Kayserili, Ellen van Beusekom, Sevim Balci, Wim Brussel, Flemming Skovby, Bronwyn Kerr, E. Ferda Percin, Nurten Akarsu
& Han G. Brunner doi:10.1038/78113 Abstract|Full text|PDF
(317K)
Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasiapp427 - 430 Koji Suzuki, Diane Hu, Tania Bustos, Joel Zlotogora, Antonio Richieri-Costa, Jill A. Helms
& Richard A. Spritz doi:10.1038/78119 Abstract|Full text|PDF
(332K)
Control of neurulation by the nucleosome assembly protein-1−like 2pp431 - 435 Ute C. Rogner, Demetri D. Spyropoulos, Nicolas Le Novère, Jean-Pierre Changeux
& Philip Avner doi:10.1038/78124 Abstract|Full text|PDF
(1,032K)
Molecular breeding of virusespp436 - 439 Nay-Wei Soong, Laurel Nomura, Katja Pekrun, Margaret Reed, Liana Sheppard, Glenn Dawes
& Willem P.C. Stemmer doi:10.1038/78132 Abstract|Full text|PDF
(245K)
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A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mousepp440 - 443 Patrick M. Nolan, Jo Peters, Mark Strivens, Derek Rogers, Jim Hagan, Nigel Spurr, Ian C. Gray, Lucie Vizor, Debra Brooker, Elaine Whitehill, Rebecca Washbourne, Tertius Hough, Simon Greenaway, Mazda Hewitt, Xinhong Liu, Stefan McCormack, Karen Pickford, Rachael Selley, Christine Wells, Zuzanna Tymowska-Lalanne, Phil Roby, Peter Glenister, Claire Thornton, Caroline Thaung, Julie-Anne Stevenson, Ruth Arkell, Philomena Mburu, Rachel Hardisty, Amy Kiernan, Alexandra Erven, Karen P. Steel, Stephanie Voegeling, Jean-Louis Guenet, Carole Nickols, Ramin Sadri, Mahmood Naase, Adrian Isaacs, Kay Davies, Mick Browne, Elizabeth M.C. Fisher, Jo Martin, Sohaila Rastan, Steve D.M. Brown
& Jackie Hunter doi:10.1038/78140 Abstract|Full text|PDF
(484K)
Genome-wide, large-scale production of mutant mice by ENU mutagenesispp444 - 447 Martin Hrabé de Angelis, Heinrich Flaswinkel, Helmut Fuchs, Birgit Rathkolb, Dian Soewarto, Susan Marschall, Stephan Heffner, Walter Pargent, Kurt Wuensch, Martin Jung, André Reis, Thomas Richter, Francesca Alessandrini, Thilo Jakob, Edith Fuchs, Helmut Kolb, Elisabeth Kremmer, Karlheinz Schaeble, Boris Rollinski, Adelbert Roscher, Christoph Peters, Thomas Meitinger, Tim Strom, Thomas Steckler, Florian Holsboer, Thomas Klopstock, Florian Gekeler, Catherine Schindewolf, Thomas Jung, Karen Avraham, Heidrun Behrendt, Johannes Ring, Andreas Zimmer, Klaus Schughart, Klaus Pfeffer, Eckhard Wolf
& Rudi Balling doi:10.1038/78146 Abstract|Full text|PDF
(340K)
|Supplementary Information
Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4pp448 - 452 Joy Y. Wu, Thomas J. Ribar, David E. Cummings, Kimberly A. Burton, G. Stanley McKnight
& Anthony R. Means doi:10.1038/78153 Abstract|Full text|PDF
(1,214K)
Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functionspp453 - 457 Chester W. Brown, Dianne E. Houston-Hawkins, Teresa K. Woodruff
& Martin M. Matzuk doi:10.1038/78161 Abstract|Full text|PDF
(2,588K)
Efficient and accurate replication in the presence of 7,8-dihydro-8-oxoguanine
by DNA polymerase pp458 - 461 Lajos Haracska, Sung-Lim Yu, Robert E. Johnson, Louise Prakash
& Satya Prakash doi:10.1038/78169 Abstract|Full text|PDF
(221K)
Mutational hot spot within a new RPGR exon in X-linked retinitis pigmentosapp462 - 466 Raf Vervoort, Alan Lennon, Alan C. Bird, Brian Tulloch, Richard Axton, Maria G. Miano, Alfons Meindl, Thomas Meitinger, Alfredo Ciccodicola
& Alan F. Wright doi:10.1038/78182 Abstract|Full text|PDF
(1,661K)
|Supplementary Information
kinase 3, is mutated in patients with Wolcott-Rallison syndrome
