Reward signals are widespread in the brain, but why? A study now identifies an important difference in the reward signals encoded by the neurons in the primate anterior cingulate and orbitofrontal cortices during decision making, suggesting that reward-related activity in these areas is shaped by different contextual factors.
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References
Thorndike, E.W. Animal Intelligence (Macmillan, 1911).
Kennerley, S.W., Behrens, T.E.J. & Wallis, J.D. Nat. Neurosci. 14, 1581–1589 (2011).
Wallis, J.D. & Kennerley, S.W. Curr. Opin. Neurobiol. 20, 191–198 (2010).
Sutton, R.S. & Barto, A.G. Reinforcement Learning: an Introduction (MIT Press, 1998).
Schultz, W. J. Neurophysiol. 80, 1–27 (1998).
Kim, H., Sul, J.H., Huh, N., Lee, D. & Jung, M.W. J. Neurosci. 29, 14701–14712 (2009).
Matsumoto, M. & Hikosaka, O. Nature 447, 1111–1115 (2007).
Matsumoto, M., Matsumoto, K., Abe, H. & Tanaka, K. Nat. Neurosci. 10, 647–656 (2007).
Seo, H. & Lee, D. J. Neurosci. 27, 8366–8377 (2007).
Padoa-Schioppa, C. J. Neurosci. 29, 14004–14014 (2009).
Kobayashi, S., Pindo de Carvalho, O. & Schultz, W. J. Neurosci. 30, 534–544 (2010).
Takahashi, Y.K. et al. Neuron 62, 269–280 (2009).
Sul, J.H., Kim, H., Huh, N., Lee, D. & Jung, M.W. Neuron 66, 449–460 (2010).
Behrens, T.E., Woolrich, M.W., Walton, M.E. & Rushworth, M.F. Nat. Neurosci. 10, 1214–1221 (2007).
Walton, M.E., Behrens, T.E., Buckley, M.J., Rudebeck, P.H. & Rushworth, M.F. Neuron 65, 927–939 (2010).
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Lee, D. It's a pleasure: a tale of two cortical areas. Nat Neurosci 14, 1491–1492 (2011). https://doi.org/10.1038/nn.2981
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DOI: https://doi.org/10.1038/nn.2981