Review

Nature Clinical Practice Cardiovascular Medicine (2006) 3, 276-282
doi:10.1038/ncpcardio0509  
Received 8 July 2005 | Accepted 27 October 2005

Mechanisms of Disease: genetic mechanisms of atrial fibrillation

Robert Roberts

Correspondence University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, ON K1Y 4W7, Canada

Email
 rroberts@ottawaheart.ca

Atrial fibrillation is the most common cause of arrhythmia, but the reason it occurs is not always apparent. Despite many efforts, the molecular basis for atrial fibrillation is still unclear. Genetic features of the disorder are, however, being elucidated. Robert Roberts provides here an overview of the major mutation findings so far.

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