Giorgia Nardone, Jorge Oliver-De La Cruz et al.

YAP regulates cell mechanics by controlling focal adhesion assembly

Browse Articles

  • Article | | open

    STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and provide a mechanism for its requirement in antigen cross-presentation.

    • Paula Nunes-Hasler
    • , Sophia Maschalidi
    • , Carla Lippens
    • , Cyril Castelbou
    • , Samuel Bouvet
    • , Daniele Guido
    • , Flavien Bermont
    • , Esen Y. Bassoy
    • , Nicolas Page
    • , Doron Merkler
    • , Stéphanie Hugues
    • , Denis Martinvalet
    • , Bénédicte Manoury
    •  & Nicolas Demaurex
  • Article | | open

    PD-L1 is upregulated in many cancers due to exogenous cellular stress. Here the authors show that PD-L1 is upregulated in response to DNA double strand breaks via STAT and IRF1 signalling.

    • Hiro Sato
    • , Atsuko Niimi
    • , Takaaki Yasuhara
    • , Tiara Bunga Mayang Permata
    • , Yoshihiko Hagiwara
    • , Mayu Isono
    • , Endang Nuryadi
    • , Ryota Sekine
    • , Takahiro Oike
    • , Sangeeta Kakoti
    • , Yuya Yoshimoto
    • , Kathryn D. Held
    • , Yoshiyuki Suzuki
    • , Koji Kono
    • , Kiyoshi Miyagawa
    • , Takashi Nakano
    •  & Atsushi Shibata
  • Article | | open

    Hemispherical format has been adopted in camera systems to better mimic human eyes, yet the current designs rely on complicated fabrications. Here, Zhang et al. show an origami-inspired approach that enables planar silicon-based photodetector arrays to reshape into concave or convex geometries.

    • Kan Zhang
    • , Yei Hwan Jung
    • , Solomon Mikael
    • , Jung-Hun Seo
    • , Munho Kim
    • , Hongyi Mi
    • , Han Zhou
    • , Zhenyang Xia
    • , Weidong Zhou
    • , Shaoqin Gong
    •  & Zhenqiang Ma
  • Article | | open

    Learning about a rewarded outcome is complicated by the fact that a choice often incorporates multiple features with differing association with the reward. Here the authors demonstrate that feature-based learning is an efficient and adaptive strategy in dynamically changing environments.

    • Shiva Farashahi
    • , Katherine Rowe
    • , Zohra Aslami
    • , Daeyeol Lee
    •  & Alireza Soltani
  • Article | | open

    There is a need for improved in vitro models of host-microbe interactions in the lung. Here, Barkal et al. present a microscale organotypic model of the human bronchiole for studying pulmonary infection, including volatile compound communication between microbial populations and host cells.

    • Layla J. Barkal
    • , Clare L. Procknow
    • , Yasmín R. Álvarez-García
    • , Mengyao Niu
    • , José A. Jiménez-Torres
    • , Rebecca A. Brockman-Schneider
    • , James E. Gern
    • , Loren C. Denlinger
    • , Ashleigh B. Theberge
    • , Nancy P. Keller
    • , Erwin Berthier
    •  & David J. Beebe
  • Article | | open

    Exosomes are known to contain microRNAs (miRs). Here the authors show that dorsal root ganglion neurons release exosomes containing miR-21-5p, which contributes to inflammatory cell recruitment following peripheral nerve injury.

    • Raffaele Simeoli
    • , Karli Montague
    • , Hefin R. Jones
    • , Laura Castaldi
    • , David Chambers
    • , Jayne H. Kelleher
    • , Valentina Vacca
    • , Thomas Pitcher
    • , John Grist
    • , Hadil Al-Ahdal
    • , Liang-Fong Wong
    • , Mauro Perretti
    • , Johnathan Lai
    • , Peter Mouritzen
    • , Paul Heppenstall
    •  & Marzia Malcangio

Natureevents Directory