Heparin is an anionic polysaccharide that has tremendous clinical importance as an anticoagulant. Several dyes have been developed that can detect heparin, and the latest example — named Mallard Blue — has now been shown to have excellent sensing properties under biologically relevant conditions.
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R.S. would like to acknowledge support from National Institutes of Health (R37 GM057073-13).
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Shriver, Z., Sasisekharan, R. Blue-chip binding. Nature Chem 5, 644–646 (2013). https://doi.org/10.1038/nchem.1701
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DOI: https://doi.org/10.1038/nchem.1701
