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| Opinion |  Top |
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| Editorials |
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Knee-jerk response p1223
doi:10.1038/82252
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(69K)
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Therapeutic space invaders p1223
doi:10.1038/82254
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| Commentary |
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Avoiding Frankendrugs p1225
Peter A. Singer
& Abdallah S. Daar
doi:10.1038/82256
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| Correspondence |
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Direct action p1227
Janet Cotter-Howells
doi:10.1038/82258
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(82K)
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Cloned pig litter update p1227
Michael D. Bishop
doi:10.1038/82261
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(82K)
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Breaching principles p1227
Giuseppe Benagiano
doi:10.1038/82263
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(82K)
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| In Brief | Top |
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| Business and Regulatory News |
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GMO roundup p1229
John Hodgson
doi:10.1038/82265
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(65K)
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Aclara found guilty p1229
Aaron Bouchie
doi:10.1038/82267
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(65K)
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Mouse genome in 2001 p1229
Aaron Bouchie
doi:10.1038/82269
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(65K)
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Invalidating patents p1229
Michael Francisco
doi:10.1038/82271
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(65K)
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Italian minister axes GMOs p1229
Anna Meldolesi
doi:10.1038/82273
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(65K)
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Gelsingers, UPenn settle suit p1230
Jeffrey Fox
doi:10.1038/82275
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(61K)
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Corixa buys Coulter p1230
Liz Fletcher
doi:10.1038/82277
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(61K)
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Monsanto IPOs again p1230
Aaron Bouchie
doi:10.1038/82279
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(61K)
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Affymetrix infringes p1230
Aaron Bouchie
doi:10.1038/82281
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(61K)
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Research collaborations p1230
doi:10.1038/82283
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| Research News |
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Red fluorescent protein structure p1231
Andrew Marshall
doi:10.1038/82286
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(82K)
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Defensin stimulant p1231
Alan Dove
doi:10.1038/82289
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(82K)
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Stem cells hunt tumors p1231
Alan Dove
doi:10.1038/82291
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(82K)
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Chromosomal checkup p1231
Aaron Bouchie
doi:10.1038/82293
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(82K)
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Artificial blood p1231
Alan Dove
doi:10.1038/82295
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(82K)
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| This Month in Biotechnology |
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Modulating protein stability p1232
Meeghan Sinclair
doi:10.1038/82297
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(74K)
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A map of the protein world p1232
Meeghan Sinclair
doi:10.1038/82299
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Evolving antibodies in a test tube p1232
Natalie DeWitt
doi:10.1038/82301
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(74K)
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Gene regulation in flux p1232
Natalie DeWitt
doi:10.1038/82303
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(74K)
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Ramping up antigen presentation p1232
Meeghan Sinclair
doi:10.1038/82305
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(74K)
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Microarrays—a closer look? p1232
Meeghan Sinclair
doi:10.1038/82307
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Evolving sturdier gene therapy vectors p1233
Judy Jamison
doi:10.1038/82310
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(67K)
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Gene amplification for plants p1233
Natalie DeWitt
doi:10.1038/82312
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(67K)
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Crop fungal protection p1233
Judy Jamison
doi:10.1038/82314
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(67K)
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Brighter aptamers for biosensing p1233
Natalie DeWitt
doi:10.1038/82317
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Technical Reports p1233
Meeghan Sinclair
doi:10.1038/82319
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(67K)
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Technical Reports p1233
Natalie DeWitt
doi:10.1038/82321
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(67K)
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Review p1233
Andrew Marshall
doi:10.1038/82323
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(67K)
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| Analysis | Top |
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| Business and Regulatory News |
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Company, academics argue over data p1235
Eric Niiler
doi:10.1038/82325
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(64K)
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First Genetic Trust banks on genes p1236
John Hodgson
doi:10.1038/82327
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(61K)
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Sweeping bioethical reform proposals contemplated for trials p1237
Jeffrey L. Fox
doi:10.1038/82329
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(61K)
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Cantab failure shows need for wide portfolio p1238
Liz Fletcher
doi:10.1038/82331
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(62K)
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HGS targets patent-expiring drugs pp1238 - 1239
Tom Hollon
doi:10.1038/82333
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(72K)
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Chiral drugs viable, despite failure pp1239 - 1240
Emma Dorey
doi:10.1038/82335
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Dutch bill unlikely to revive industry p1240
Marianne Heselmans
doi:10.1038/82337
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(62K)
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| News and Views |
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New tools for an old workhorse pp1241 - 1242
Kenneth E. Rudd
doi:10.1038/82339
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(74K)
See also: Research by Selinger et al. |
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Protein networks—built by association pp1242 - 1243
Melanie L. Mayer
& Philip Hieter
doi:10.1038/82342
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(70K)
See also: Research by Schwikowski et al. |
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Viral vectors do the DNA shuffle pp1244 - 1245
Atsushi Miyanohara
& Theodore Friedmann
doi:10.1038/82345
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(94K)
See also: Research by Powell et al. |
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Triplex technology takes off pp1245 - 1246
Carine Giovannangeli
& Claude Hélène
doi:10.1038/82348
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(75K)
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| Feature | Top |
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The changing marketplace of bioinformatics pp1247 - 1249
Paolo P. Saviotti, Marie-Angèle deLooze, Sylvie Michelland
& David Catherine
doi:10.1038/82351
Abstract | Full text | PDF
(77K)
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| Research | Top |
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| Review |
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Applications of display technology in protein analysis pp1251 - 1256
Min Li
doi:10.1038/82355
Abstract | Full text | PDF
(149K)
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| Articles |
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A network of protein−protein interactions in yeast pp1257 - 1261
Benno Schwikowski, Peter Uetz
& Stanley Fields
doi:10.1038/82360
Abstract | Full text | PDF
(175K)
| Supplementary Information
See also: Analysis by Mayer & Hieter |
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RNA expression analysis using a 30 base pair resolution Escherichia
coli genome array pp1262 - 1268
Douglas W. Selinger, Kevin J. Cheung, Rui Mei, Erik M. Johansson, Craig S. Richmond, Frederick R. Blattner, David J. Lockhart
& George M. Church
doi:10.1038/82367
Abstract | Full text | PDF
(278K)
See also: Analysis by Rudd |
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Enhanced major histocompatibility complex class I-dependent presentation
of antigens modified with cationic and fusogenic peptides pp1269 - 1272
Reiner Laus, Thomas J. Graddis, Itzhak Hakim
& Damir Vidovic
doi:10.1038/82377
Abstract | Full text | PDF
(104K)
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Efficient nonviral transfection of dendritic cells and their use for
in vivo immunization pp1273 - 1278
Alistair S. Irvine, Peter K.E. Trinder, David L. Laughton, Helen Ketteringham, Ruth H. McDermott, Sophie C.H. Reid, Adrian M.R. Haines, Abdu Amir, Rhonda Husain, Rajeev Doshi, Lawrence S. Young
& Andrew Mountain
doi:10.1038/82383
Abstract | Full text | PDF
(193K)
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Breeding of retroviruses by DNA shuffling for improved stability and
processing yields pp1279 - 1282
Sharon K. Powell, Michele A. Kaloss, Anne Pinkstaff, Rebecca McKee, Irina Burimski, Michael Pensiero, Edward Otto, Willem P.C. Stemmer
& Nay-Wei Soong
doi:10.1038/82391
Abstract | Full text | PDF
(120K)
| Supplementary Information
See also: Analysis by Miyanohara & Friedmann |
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Increasing galactose consumption by Saccharomyces cerevisiae through
metabolic engineering of the GAL gene regulatory network pp1283 - 1286
Simon Ostergaard, Lisbeth Olsson, Mark Johnston
& Jens Nielsen
doi:10.1038/82400
Abstract | Full text | PDF
(116K)
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Picomolar affinity antibodies from a fully synthetic naive library selected
and evolved by ribosome display pp1287 - 1292
Jozef Hanes, Christiane Schaffitzel, Achim Knappik
& Andreas Plückthun
doi:10.1038/82407
Abstract | Full text | PDF
(202K)
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In vitro selection of signaling aptamers pp1293 - 1297
Sulay Jhaveri, Manjula Rajendran
& Andrew D. Ellington
doi:10.1038/82414
Abstract | Full text | PDF
(217K)
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A ubiquitin-based tagging system for controlled modulation of protein
stability pp1298 - 1302
Jeffrey H. Stack, Michael Whitney, Steven M. Rodems
& Brian A. Pollok
doi:10.1038/82422
Abstract | Full text | PDF
(148K)
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Tobacco ribosomal DNA spacer element stimulates amplification and expression
of heterologous genes pp1303 - 1306
Nikolai Borisjuk, Ludmyla Borisjuk, Slavko Komarnytsky, Sofia Timeva, Vera Hemleben, Yuri Gleba
& Ilya Raskin
doi:10.1038/82430
Abstract | Full text | PDF
(173K)
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Fungal pathogen protection in potato by expression of a plant defensin
peptide pp1307 - 1310
Ai-Guo Gao, Salim M. Hakimi, Cindy A. Mittanck, Yonnie Wu, B. Mark Woerner, David M. Stark, Dilip M. Shah, Jihong Liang
& Caius M.T. Rommens
doi:10.1038/82436
Abstract | Full text | PDF
(190K)
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| Technical Reports |
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Stable correction of a genetic deficiency in human cells by an episome
carrying a 115 kb genomic transgene pp1311 - 1314
Richard Wade-Martins, Robert E. White, Hiroshi Kimura, Peter R. Cook
& Michael R. James
doi:10.1038/82444
Abstract | Full text | PDF
(165K)
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DNA cloning by homologous recombination in Escherichia coli pp1314 - 1317
Youming Zhang, Joep P.P. Muyrers, Giuseppe Testa
& A. Francis Stewart
doi:10.1038/82449
Abstract | Full text | PDF
(104K)
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| Erratum | Top |
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Research Errata p1318
doi:10.1038/82454
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(84K)
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| Corrigendum | Top |
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Research Corrigendum p1318
doi:10.1038/82458
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(84K)
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| Resources | Top |
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| Patents |
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Moving the gene patent debate forward pp1319 - 1320
E. Richard Gold
doi:10.1038/82460
Abstract | Full text | PDF
(67K)
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Recent patents in phage display p1321
doi:10.1038/82462
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(53K)
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| People |
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Promotions, advancements p1322
doi:10.1038/82465
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(64K)
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| New Products |
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New Products p1323
doi:10.1038/82468
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(153K)
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| Index | Top |
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2000 Subject index — Volume 18 pp1325 - 1330
doi:10.1038/82476
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(103K)
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2000 Author index — Volume 18 pp1330 - 1333
doi:10.1038/82478
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(78K)
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