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Mapping higher-order RNA structures and intermolecular RNA–RNA interactions throughout the transcriptome is critical for understanding RNA functions. We developed KARR-seq, a chemical-assisted RNA proximity capture and sequencing technology that enables sensitive and accurate detection of the RNA structurome and functional RNA–RNA interactions.
Sophisticated genome editing tools to tweak multiple genes in one step are forging a first-of-its-kind generation of universal CAR T therapeutics, while ‘epitope-edited’ and virus-free manufacturing aim to democratize CAR T cells’ clinical uptake worldwide.
Biotechnology (biotech) clusters have evolved over time. Being a top biotech region in the early years 1978–1990 still positively correlates with the cluster’s biotech strength decades later. An entrepreneurial orientation of scientific actors as well as a variety of networks with partners outside the cluster both contribute to sustained biotech activity.
More can be done to diversify the AI innovation ecosystem, especially in the emerging field of biotechnology AI, where women’s participation is associated with substantial value.
An intensive summer training program increased enrollment in a Master of Science in Biotechnology degree program, increasing awareness and opportunities among under-represented and underserved groups as a first step to transforming the biotech industry.
An integrated wearable and wireless ultrasound device enables the continuous monitoring of physiological information from tissues in moving individuals.