Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Organoids

Eavesdropping on brain organoids

Nature Biotechnology (2024)Cite this article

Subjects

A basket-like device records the electrical activity of neural organoids over months of maturation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Kirigami electronics cradle and monitor the development of human assembloids.

References

  1. Yang, X. et al. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-02081-3 (2024).

  2. Lancaster, M. A. et al. Nature 501, 373–379 (2013).

    Article  CAS  PubMed  Google Scholar 

  3. Paşca, A. M. et al. Nat. Methods 12, 671–678 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  4. Wilson, M. N. et al. Nat. Commun. 13, 7945 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Revah, O. et al. Nature 610, 319–326 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Miura, Y. et al. Nat. Biotechnol. 38, 1421–1430 (2020).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Quadrato, G. et al. Nature 545, 48–53 (2017).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Trujillo, C. A. et al. Cell Stem Cell 25, 558–569.e7 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Park, Y. et al. Sci. Adv. 7, eabf9153 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  10. Balci, F. et al. Neuron 111, 604–605 (2023).

    Article  CAS  PubMed  Google Scholar 

  11. Qian, X., Song, H. & Ming, G. L. Development 146, dev166074 (2019).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Neural Dynamics & Cognition, The Rockefeller University, New York, NY, USA

    James Newton Brandt & Priya Rajasethupathy

Authors
  1. James Newton Brandt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Priya Rajasethupathy
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Priya Rajasethupathy.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Brandt, J.N., Rajasethupathy, P. Eavesdropping on brain organoids. Nat Biotechnol (2024). https://doi.org/10.1038/s41587-024-02128-z

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41587-024-02128-z

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research