Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Metabolism

Let them eat fat

A specialist neuron uses an intriguing process to help control the body's response to hunger. A lipid pathway involving the breakdown of cellular components regulates the expression of a neuropeptide that affects feeding and body weight.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Fatty-acid regulation of starvation-sensitive neurons.

References

  1. Kaushik, S. et al. Cell Metab. 14, 173–183 (2011).

    Article  CAS  Google Scholar 

  2. Luquet, S., Perez, F. A., Hnasko, T. S. & Palmiter, R. D. Science 310, 683–685 (2005).

    Article  ADS  CAS  Google Scholar 

  3. Aponte, Y., Atasoy, D. & Sternson, S. M. Nature Neurosci. 14, 351–355 (2011).

    Article  CAS  Google Scholar 

  4. Krashes, M. J. et al. J. Clin. Invest. 121, 1424–1428 (2011).

    Article  CAS  Google Scholar 

  5. Singh, R. et al. Nature 458, 1131–1135 (2009).

    Article  ADS  CAS  Google Scholar 

  6. Andrews, Z. B. et al. Nature 454, 846–851 (2008).

    Article  ADS  CAS  Google Scholar 

  7. Kitamura, T. et al. Nature Med. 12, 534–540 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Scott M. Sternson.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sternson, S. Let them eat fat. Nature 477, 166–167 (2011). https://doi.org/10.1038/477166a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/477166a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing