Table of contents
Volume 403 Number 6767 pp229-344
(this content only available online) indicates content that is available online only
Opinion
In praise of open software p229
Freely available software, developed by researchers, is good for science and keeps commercial companies on their toes. In an era of quasi-monopolies, research institutions should encourage it.
doi:10.1038/35002141
A step up for a few postdocs p229
One initiative in one Dutch institute, born out of necessity, provides an example to follow.
doi:10.1038/35002143
News
Celera genome licensing terms spark concerns over 'monopoly' p231
Declan Butler and Paul Smaglik
doi:10.1038/35002145
Merger of Glaxo Wellcome and SmithKline Beecham creates pharmaceutical giant p232
Alison Abbott
doi:10.1038/35002148
NASA ponders termination of gamma-ray observatory p232
Tony Reichhardt
doi:10.1038/35002151
Global-warming sceptics left out in the cold p233
Colin Macilwain
doi:10.1038/35002154
Diversity convention in the balance p233
Colin Macilwain
doi:10.1038/35002156
DIY microarrayers promise DNA chips with everything p234
Rex Dalton
doi:10.1038/35002159
Australian university chiefs attack plans for research funding p234
Peter Pockley
doi:10.1038/35002162
Dutch institute forced to respond to crisis in recruitment of postdoctoral researchers p235
Natasha Loder
doi:10.1038/35002164
Appointment of UK food standards chief under fire p235
Natasha Loder
doi:10.1038/35002168
Mouse geneticists call for unified rules of exchange p236
Alison Abbott
doi:10.1038/35002171
Business lobby set to take EPA to court over data access p236
Colin Macilwain
doi:10.1038/35002174
NIH under fire over gene-therapy trials... p237
Meredith Wadman
doi:10.1038/35002176
...as panel seeks help for trial host nations p237
Paul Smaglik
doi:10.1038/35002179
Correspondence
Local data are vital to worldwide conservation p241
Jon Paul Rodríguez, Gillian Ashenfelter, Franklin Rojas-Suárez, Juan Javier García Fernández, Luis Suárez and Andrew P. Dobson
doi:10.1038/35002183
There's a place for the theory of everything p241
John Ellis
doi:10.1038/35002186
ECT damage is easy to find if you look for it p242
Peter Sterling
doi:10.1038/35002188
Full effects of oil rigs on corals are not yet known p242
J. M. Roberts
doi:10.1038/35002190
Cover adds fuel to the fire in evolution battle p242
Gary C. Harris and Martina Königer
doi:10.1038/35002192
Commentary
Seeking the great transition p243
Environmentally sustainable economies are unachievable without enhanced participation of the private sector. Scientists must facilitate this process.
doi:10.1038/35002194
Book Reviews
Is the sky made from pi? p247
Our concept of the Universe is prey to various numerical interpretations.
Frank Wilczek reviews Just Six Numbers: The Deep Forces that Shape the Universe by Martin Rees and The Nine Numbers of the Universe by Michael Rowan-Robinson
doi:10.1038/35002196
Quasars, nebulae, and more p248
doi:10.1038/35002199
Arctic antics p248
Douglas Palmer reviews Ice Finders: How a Poet, a Professor, and a Politician Discovered the Ice Age by Edmund Blair Bolles
doi:10.1038/35002202
The Osler magic revisited p249
W. F. Bynum reviews William Osler: A Life in Medicine by Michael Bliss
doi:10.1038/35002205
New in paperback p250
doi:10.1038/35002208
Seeing the world in a mote of dust p250
Ralph Lewin reviews Dust: A History of the Small and the Invisible by Joseph A. Amato
doi:10.1038/35002210
Millennium Essay
Tycho and the ton of gold p251
Why a brilliantly conceived research programme failed.
Owen Gingerich
doi:10.1038/35002212
Futures
Cognitive ability and the light bulb p253
The road to the stars has also illuminated the human mind
Brian Aldiss
doi:10.1038/35002217
News and Views
Signal transduction: A central control for cell growth p255
The identification of an unexpected function for the mitogen-activated protein kinase — the synthesis of DNA and RNA — opens up yet another route by which this multifaceted enzyme can influence cellular growth.
Alan J. Whitmarsh and Roger J. Davis
doi:10.1038/35002220
Quantum physics: Engineering decoherence p256
Wolfgang P. Schleich
doi:10.1038/35002223
Neurobiology: Finding the lost target p257
Martin E. Schwab
doi:10.1038/35002226
100 and 50 years ago p259
doi:10.1038/35002230
Atmospheric chemistry: Better budgets for methyl halides? p260
James H. Butler
doi:10.1038/35002232
Evolutionary biology: Protamine wars p261
Andrew G. Clark and Alberto Civetta
doi:10.1038/35002236
Daedalus: States of non-mind p263
David Jones
doi:10.1038/35002239
erratum: A tale of ends p263
Victoria Lundblad
doi:10.1038/35002241
Obituary: Robert A. Swanson (1947–99) p264
David V. Goeddel and Arthur D. Levinson
doi:10.1038/35002244
Brief Communications
Ultrasonic hearing in nocturnal butterflies p265
Hedylids have ultrasound-sensitive ears on their wings to help them avoid bats.
Jayne E. Yack and James H. Fullard
doi:10.1038/35002247
Alloys: Atomic structure of the quasicrystal Al72Ni20Co8 p266
Yanfa Yan and Stephen J. Pennycook
doi:10.1038/35002251
First paragraph | Full Text | PDF (445K)
Atomic structure of the quasicrystal Al72Ni20Co8 p267
Paul J. Steinhardt, H.-C. Jeong, K. Saitoh, M. Tanaka, E. Abe and A. P. Tsai
doi:10.1038/35002255
Biological rhythms: Circadian clocks limited by noise p267
Naama Barkai and Stanislas Leibler
doi:10.1038/35002258
First paragraph | Full Text | PDF (201K)
Articles
Decoherence of quantum superpositions through coupling to engineered reservoirs p269
C. J. Myatt, B. E. King, Q. A. Turchette, C. A. Sackett, D. Kielpinski, W. M. Itano, C. Monroe and D. J. Wineland
doi:10.1038/35002001
Abstract | Full Text | PDF (233K)
See also: News and Views by Schleich
Direct protein–protein coupling enables cross-talk between dopamine
D5 and 
-aminobutyric acid A receptors p274
Fang Liu, Qi Wan, Zdenek B. Pristupa, Xian-Min Yu, Yu Tian Wang and Hyman B. Niznik
doi:10.1038/35002014
Abstract | Full Text | PDF (1,422K)
Letters to Nature
Polarization rotation mechanism for ultrahigh electromechanical response in single-crystal piezoelectrics p281
Huaxiang Fu and Ronald E. Cohen
doi:10.1038/35002022
First paragraph | Full Text | PDF (174K)
Dynamics of supercooled water in confined geometry p283
R. Bergman and J. Swenson
doi:10.1038/35002027
First paragraph | Full Text | PDF (309K)
Molecular imprinting of bulk, microporous silica p286
Alexander Katz and Mark E. Davis
doi:10.1038/35002032
First paragraph | Full Text | PDF (306K)
Biomimetic synthesis of ordered silica structures mediated by block copolypeptides p289
Jennifer N. Cha, Galen D. Stucky, Daniel E. Morse and Timothy J. Deming
doi:10.1038/35002038
First paragraph | Full Text | PDF (269K)
Natural methyl bromide and methyl chloride emissions from coastal salt marshes p292
Robert C. Rhew, Benjamin R. Miller and Ray F. Weiss
doi:10.1038/35002043
First paragraph | Full Text | PDF (253K)
See also: News and Views by Butler
A strong source of methyl chloride to the atmosphere from tropical coastal land p295
Y. Yokouchi, Y. Noijiri, L. A. Barrie, D. Toom-Sauntry, T. Machida, Y. Inuzuka, H. Akimoto, H.-J. Li, Y. Fujinuma and S. Aoki
doi:10.1038/35002049
First paragraph | Full Text | PDF (1,069K)
See also: News and Views by Butler
Halocarbons produced by natural oxidation processes during degradation of organic matter p298
F. Keppler, R. Eiden, V. Niedan, J. Pracht and H. F. Schöler
doi:10.1038/35002055
First paragraph | Full Text | PDF (207K)
See also: News and Views by Butler
Annual fluxes of carbon from deforestation and regrowth in the Brazilian Amazon p301
R. A. Houghton, D. L. Skole, Carlos A. Nobre, J. L. Hackler, K. T. Lawrence and W H. Chomentowski
doi:10.1038/35002062
First paragraph | Full Text | PDF (281K)
Rapid evolution of male reproductive genes in the descent of man p304
Gerald J. Wyckoff, Wen Wang and Chung-I Wu
doi:10.1038/35002070
First paragraph | Full Text | PDF (291K)
See also: News and Views by Clark & Civetta
Voice-selective areas in human auditory cortex p309
Pascal Belin, Robert J. Zatorre, Philippe Lafaille, Pierre Ahad and Bruce Pike
doi:10.1038/35002078
First paragraph | Full Text | PDF (301K)
Functional regeneration of sensory axons into the adult spinal cord p312
Matt S. Ramer, John V. Priestley and Stephen B. McMahon
doi:10.1038/35002084
First paragraph | Full Text | PDF (465K)
See also: News and Views by Schwab
Glutamate release in severe brain ischaemia is mainly by reversed uptake p316
David J. Rossi, Takeo Oshima and David Attwell
doi:10.1038/35002090
First paragraph | Full Text | PDF (407K)
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications p321
Donato del Camino, Miguel Holmgren, Yi Liu and Gary Yellen
doi:10.1038/35002099
First paragraph | Full Text | PDF (342K) | Supplementary information
KIR expression on self-reactive CD8+ T cells is controlled by T-cell receptor engagement p325
Bertrand Huard and Lars Karlsson
doi:10.1038/35002105
First paragraph | Full Text | PDF (177K) | Supplementary information
Regulation of carbamoyl phosphate synthetase by MAP kinase p328
Lee M. Graves, Hedeel I. Guy, Piotr Kozlowski, Min Huang, Eduardo Lazarowski, R. Marshall Pope, Matthew A. Collins, Erik N. Dahlstrand, H. Shelton Earp, III and David R. Evans
doi:10.1038/35002111
First paragraph | Full Text | PDF (321K) | Supplementary information
See also: News and Views by Whitmarsh & Davis
The joining of ribosomal subunits in eukaryotes requires eIF5B p332
Tatyana V. Pestova, Ivan B. Lomakin, Joon H. Lee, Sang Ki Choi, Thomas E. Dever and Christopher U. T. Hellen
doi:10.1038/35002118
First paragraph | Full Text | PDF (249K)
A synthetic oscillatory network of transcriptional regulators p335
Michael B. Elowitz and Stanislas Leibler
doi:10.1038/35002125
First paragraph | Full Text | PDF (728K)
Construction of a genetic toggle switch in Escherichia coli p339
Timothy S. Gardner, Charles R. Cantor and James J. Collins
doi:10.1038/35002131
First paragraph | Full Text | PDF (1,130K) | Supplementary information
New on the Market
Sensors, safety and SPR p343
Biosensors, biochips, bioeverything.
doi:10.1038/35002261
