Opinion

Too hesitant steps forward in European collaboration p623

Researchers seeking to build projects that make the best of Europe's potential have no obvious place to turn. A new proposal should be actively encouraged by funding agencies, despite their strong reservations.

doi:10.1038/27017

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News

Nobel award stirs up debate on nitric oxide breakthrough p625

Rory Howlett

doi:10.1038/27019

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Hidden role of a gas of many parts p625

Rory Howlett

doi:10.1038/27023

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Physicists rewarded for 'fractional electrons' p626

Philip Ball

doi:10.1038/27025

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Theoretical chemistry makes its mark p626

Philip Ball

doi:10.1038/27028

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Congress warns nuclear labs of spy risk p627

Colin Macilwain

doi:10.1038/27031

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Pay crisis drives Russian scientists abroad p627

Carl Levitin

doi:10.1038/27034

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Japan may require labels on genetic food p628

Asako Saegusa

doi:10.1038/27036

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UK environment report looks to the people p628

Quirin Schiermeier

doi:10.1038/27039

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UK nuclear waste firm faces US critics p629

Colin Macilwain

doi:10.1038/27041

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Epidemiologist's funds axed after report on Californian smoking p629

Sally Lehrmann

doi:10.1038/27043

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Canadians call for tax cuts to curb the 'brain drain'... p630

David Spurgeon

doi:10.1038/27046

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... as skilled workers head for the United States p630

David Spurgeon

doi:10.1038/27048

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France abandons plan to reform national biomedical agency p630

Declan Butler

doi:10.1038/27050

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UK contract staff need help, says report p631

David Dickson

doi:10.1038/27052

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New telescope shows off its paces p631

Ehsan Masood

doi:10.1038/27054

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News in Brief p632

doi:10.1038/27057

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Correspondence

101 uses for a life sciences PhD p634

Andrew A. Bogan and Elizabeth C. Bogan

doi:10.1038/27059

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The Western front p634

Daniel Wildcat and Raymond Pierotti

doi:10.1038/27061

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Coelacanth populations may go with the flow p634

Arnold L. Gordon

doi:10.1038/27063

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Launch editor p634

Faith Rogers

doi:10.1038/27065

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News and Views

How big do stellar explosions get? p635

Eddie Baron

doi:10.1038/27067

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Human evolution:  Towards a genetic history of China p636

Alberto Piazza

doi:10.1038/27071

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Behavioural ecology:  Pick out a penguin p637

Rory Howlett

doi:10.1038/27075

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Cosmology:  New troubles for inflation? p639

Marc Kamionkowski and Andrew H. Jaffe

doi:10.1038/27078

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100 and 50 years ago p640

doi:10.1038/27081

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Photonics:  Chemistry of light p640

Stephen Battersby

doi:10.1038/27083

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Developmental biology: Cripto-analysis of embryonic codes p641

Rosa Beddington

doi:10.1038/27086

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Daedalus:  New smells for old p643

David Jones

doi:10.1038/27089

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Obituary:  Frederick Reines (1918-98) p644

Michael Moe

doi:10.1038/27091

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News and Views Feature

Calcium - a life and death signal p645

One of the most versatile and universal signalling agents in the human body is the calcium ion, Ca²⁺. How does this simple ion act during cell birth, life and death, and how does it regulate so many different cellular processes?

Michael J. Berridge, Martin D. Bootman and Peter Lipp

doi:10.1038/27094

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Science and Image

Monge's maths, Hummel's highlights p649

The type of perspective favoured in technical drawing was first used by military draughtsmen to ensure accurate fortifications. It was developed geometrically by Gaspard Monge and drawn to perfection by Johann Hummel.

Martin Kemp

doi:10.1038/27099

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Scientific Correspondence

Female gene flow stratifies Hindu castes p651

Michael J. Bamshad, W. Scott Watkins, Mary E. Dixon, Lynn B. Jorde, B. Bhaskara Rao, J. M. Naidu, B. V. Ravi Prasad, Arani Rasanayagam and Mike F. Hammer

doi:10.1038/27103

First paragraph | Full Text | PDF (176K)

Effects of progesterone or neuroactive steroid? p652

A. Leslie Morrow, Margaret J. VanDoren and Leslie L. Devaud

doi:10.1038/27106

First paragraph | Full Text | PDF (196K)

Reply:  Effects of progesterone or neuroactive steroid? p652

Sheryl S. Smith, Qi Hua Gong, Fu-Chun Hsu, Ronald S. Markowitz, J. M. H. ffrench-Mullen and Xinshe Li

doi:10.1038/27109

First paragraph | Full Text | PDF (196K)

Young wallabies get a free ride p653

R. V. Baudinette and A. A. Biewener

doi:10.1038/27111

First paragraph | Full Text | PDF (216K)

Stabilizing gaze in flying blowflies p654

C. Schilstra and J. H. van Hateren

doi:10.1038/27114

First paragraph | Full Text | PDF (179K) | Supplementary information

Book Reviews

The bird-watcher's guides to paradise p655

Jared Diamond reviews A Guide to the Birds of Wallacea by Brian J. Coates, K. David Bishop and D. Gardner and The Birds of Paradise by Clifford B. Frith and Bruce M. Beehler

doi:10.1038/27118

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Are talkers the only thinkers? p656

Karen McComb and Stuart Semple review If a Lion Could Talk: Animal Intelligence and the Evolution of Consciousness by Stephen Budiansky

doi:10.1038/27122

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Bound for the future p657

David Larbalestier reviews Handbook of Applied Superconductivity edited by Bernd Seeber

doi:10.1038/27125

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When the boat comes in p658

Linda Medlin reviews Marine Biodiversity: Patterns and Processes edited by R. F. G. Ormund, J. D. Gage and M. V. Angel

doi:10.1038/27128

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Progress

A vertebrate model of extreme physiological regulation p659

Stephen M. Secor and Jared Diamond

doi:10.1038/27131

Abstract | Full Text | PDF (213K)

Article

Radio emission from the unusual supernova 1998bw and its association with the -ray burst of 25 April 1998 p663

S. R. Kulkarni, D. A. Frail, M. H. Wieringa, R. D. Ekers, E. M. Sadler, R. M. Wark, J. L. Higdon, E. S. Phinney and J. S. Bloom

doi:10.1038/27139

Abstract | Full Text | PDF (346K)

See also: News and Views by Baron

Letters to Nature

An unusual supernova in the error box of the -ray burst of 25 April 1998 p670

T. J. Galama, P. M. Vreeswijk, J. van Paradijs, C. Kouveliotou, T. Augusteijn, H. Böhnhardt, J. P. Brewer, V. Doublier, J.-F. Gonzalez, B. Leibundgut, C. Lidman, O. R. Hainaut, F. Patat, J. Heise, J. in't Zand, K. Hurley, P. J. Groot, R. G. Strom, P. A. Mazzali, K. Iwamoto, K. Nomoto, H. Umeda, T. Nakamura, T. R. Young, T. Suzuki, T. Shigeyama, T. Koshut, M. Kippen, C. Robinson, P. de Wildt, R. A. M. J. Wijers, N. Tanvir, J. Greiner, E. Pian, E. Palazzi, F. Frontera, N. Masetti, L. Nicastro, M. Feroci, E. Costa, L. Piro, B. A. Peterson, C. Tinney, B. Boyle, R. Cannon, R. Stathakis, E. Sadler, M. C. Begam and P. Ianna

doi:10.1038/27150

First paragraph | Full Text | PDF (294K)

See also: News and Views by Baron

A hypernova model for the supernova associated with the -ray burst of 25 April 1998 p672

K. Iwamoto, P. A. Mazzali, K. Nomoto, H. Umeda, T. Nakamura, F. Patat, I. J. Danziger, T. R. Young, T. Suzuki, T. Shigeyama, T. Augusteijn, V. Doublier, J.-F. Gonzalez, H. Boehnhardt, J. Brewer, O. R. Hainaut, C. Lidman, B. Leibundgut, E. Cappellaro, M. Turatto, T. J. Galama, P. M. Vreeswijk, C. Kouveliotou, J. van Paradijs, E. Pian, E. Palazzi and F. Frontera

doi:10.1038/27155

First paragraph | Full Text | PDF (304K)

See also: News and Views by Baron

Experimental evidence for a two-dimensional quantized Hall insulator p675

M. Hilke, D. Shahar, S. H. Song, D. C. Tsui, Y. H. Xie and Don Monroe

doi:10.1038/27160

First paragraph | Full Text | PDF (255K)

Room-temperature magnetoresistance in an oxide material with an ordered double-perovskite structure p677

K.-I. Kobayashi, T. Kimura, H. Sawada, K. Terakura and Y. Tokura

doi:10.1038/27167

First paragraph | Full Text | PDF (1,415K)

Silicon-isotope composition of diatoms as an indicator of past oceanic change p680

C. L. De La Rocha, M. A. Brzezinski, M. J. DeNiro and A. Shemesh

doi:10.1038/27174

First paragraph | Full Text | PDF (272K)

Formation of atmospheric particles from organic acids produced by forests p683

Ilias G. Kavouras, Nikolaos Mihalopoulos and Euripides G. Stephanou

doi:10.1038/27179

First paragraph | Full Text | PDF (315K)

Mantle convection simulations with rheologies that generate plate-like behaviour p686

Ron Trompert and Ulrich Hansen

doi:10.1038/27185

First paragraph | Full Text | PDF (373K)

Two-dimensional matches from one-dimensional stimulus components in human stereopsis p689

Bart Farell

doi:10.1038/27192

First paragraph | Full Text | PDF (466K)

Who reads temporal information contained across synchronized and oscillatory spike trains? p693

Katrina MacLeod, Alex Bäcker and Gilles Laurent

doi:10.1038/27201

First paragraph | Full Text | PDF (538K)

Destabilization of -catenin by mutations in presenilin-1 potentiates neuronal apoptosis p698

Zhuohua Zhang, Henrike Hartmann, Viet Minh Do, Dorothee Abramowski, Christine Sturchler-Pierrat, Matthias Staufenbiel, Bernd Sommer, Marc van de Wetering, Hans Clevers, Paul Saftig, Bart De Strooper, Xi He and Bruce A. Yankner

doi:10.1038/27208

First paragraph | Full Text | PDF (707K)

Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo p702

Jixiang Ding, Lu Yang, Yu-Ting Yan, Amy Chen, Nishita Desai, Anthony Wynshaw-Boris and Michael M. Shen

doi:10.1038/27215

First paragraph | Full Text | PDF (595K)

See also: News and Views by Beddington

Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a p707

Brian A. Parr and Andrew P. McMahon

doi:10.1038/27221

First paragraph | Full Text | PDF (492K)

Spanning binding sites on allosteric proteins with polymer-linked ligand dimers p710

Richard H. Kramer and Jeffrey W. Karpen

doi:10.1038/27227

First paragraph | Full Text | PDF (278K) | Supplementary information

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor p713

Yutaka Kato, Richard I. Tapping, Shuang Huang, Mark H. Watson, Richard J. Ulevitch and Jiing-Dwan Lee

doi:10.1038/27234

First paragraph | Full Text | PDF (339K)

Suppression of auxin signal transduction by a MAPK cascade in higher plants p716

Yelena Kovtun, Wan-Ling Chiu, Weike Zeng and Jen Sheen

doi:10.1038/27240

First paragraph | Full Text | PDF (513K)

Ribonuclease E is a 5'-end-dependent endonuclease p720

George A. Mackie

doi:10.1038/27246

First paragraph | Full Text | PDF (329K)

erratum:  Subsurface charge accumulation imaging of a quantum Hall liquid p724

S. H. Tessmer, P. I. Glicofridis, R. C. Ashoori, L. S. Levitov and M. R. Melloch

doi:10.1038/27252

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New on the Market

Ways to handle DNA p725

The molecular biology tools presented here include microchip array analysers and labels, telomeric probes, cloning kits for cosmic library construction and a system for quantifying and analysing fluorescently labelled nucleic acids.

compiled by Brendan Horton from information provided by the manufacturers.

doi:10.1038/27257

Full Text | PDF (278K)