Table of contents
Volume 392 Number 6671 pp1-108
Opinion
Reforms on a knife edge p1
Frustration among French researchers at an apparent slowing down in promised reforms threatens to undermine an essential process. A less abrasive attitude on the government's part is essential.
doi:10.1038/31985
Lewis and Clark, lost in the wilderness? p1
The abandonment of a privately managed satellite should encourage sharper thinking about such ventures.
doi:10.1038/31987
News
Max Planck Society faces 'hard decisions' to uphold standards p3
Alison Abbott
doi:10.1038/31989
UK plays safe on risks from blood products p3
Asako Saegusa
doi:10.1038/31992
Russia invests in a 'revolutionary' disc p4
Carl Levitin
doi:10.1038/31994
India urged to act against leptospirosis p4
K. S. Jayaraman
doi:10.1038/31997
Clark's demise halts NASA experiment in remote sensing p5
Tony Reichhardt
doi:10.1038/31999
Survey results boost calls for new teaching efforts p5
Colin Macilwain
doi:10.1038/32001
Privacy bill under fire from researchers p6
Meredith Wadman
doi:10.1038/32004
Biomedical billions go under the microscope p6
Meredith Wadman
doi:10.1038/32007
Cuts reversed in Canada's new budget p7
David Spurgeon
doi:10.1038/32009
Australia urged to avert collapse of university science p7
Peter Pockley
doi:10.1038/32011
News Analysis
Jury still undecided on French reforms p8
Hopes were high within the French research community when Claude Allègre was appointed minister of research last year. But a good start has given way to frustration with the slow speed of change.
Declan Butler
doi:10.1038/32014
Researchers challenge biomedical plans p9
Declan Butler
doi:10.1038/32018
Correspondence
Xenotransplants: proceed with caution p11
A. S. Daar
doi:10.1038/32023
Search for consensus on genetic engineering p13
Michael Altmann
doi:10.1038/32025
Growing benefits of biotechnology p13
Gordon Conway
doi:10.1038/32027
Benefits and dangers of genetic tests p14
Harry Ostrer
doi:10.1038/32029
About face p14
Jonathan Cole
doi:10.1038/32031
News and Views
A paradigm gets shifty p15
W. Ford Doolittle
doi:10.1038/32033
Solar System: Two shades beyond Neptune p16
Clark R. Chapman
doi:10.1038/32037
Palaeobiology: Mass extinction probed p17
Charles R. Marshall
doi:10.1038/32039
100 and 50 years ago p19
doi:10.1038/32042
Cardiac physiology: A last wave from the dying heart p20
Arun V. Holden
doi:10.1038/32044
Cavitation physics: Lasers blow a bigger bubble p21
Detlef Lohse
doi:10.1038/32047
Neurodegeneration: Chaperoning brain diseases p23
William J. Welch and Pierluigi Gambetti
doi:10.1038/32049
Cosmology: A circumscribed Universe p24
Masataka Fukugita
doi:10.1038/32053
Systematics: Sequences lead to tree of worms p25
Claus Nielsen
doi:10.1038/32058
Daedalus: Fibre couplings p26
David Jones
doi:10.1038/32062
Art and Science
Vermeer's vision p27
Jan Vermeer's mastery of the use of paint was such that we see more in his pictures than is actually there. The painter achieved his illusions by using the picture as a field for perceptual exploration.
Martin Kemp
doi:10.1038/32064
Scientific Correspondence
Does acoustic testing strand whales? p29
A. Frantzis
doi:10.1038/32068
First paragraph | Full Text | PDF (181K)
Electron pairs shed light on frustrated percolation p29
P. J. van der Put
doi:10.1038/32071
First paragraph | Full Text | PDF (181K)
Synthetic ligands point to cell surface strategies p30
Eva J. Gordon, William J. Sanders and Laura L. Kiessling
doi:10.1038/32073
First paragraph | Full Text | PDF (183K)
Thyroid cancer risk to children calculated p31
P. Jacob, G. Goulko, W. F. Heidenreich, I. Likhtarev, I. Kairo, N. D. Tronko, T. I. Bogdanova, J. Kenigsberg, E. Buglova, V. Drozdovitch, A. Golovneva, E. P. Demidchik, M. Balonov, I. Zvonova and V. Beral
doi:10.1038/32076
First paragraph | Full Text | PDF (171K)
Sulphur isotope data consistency improved p32
Tyler B. Coplen and H. Roy Krouse
doi:10.1038/32080
First paragraph | Full Text | PDF (161K)
Book Reviews
Rise and fall of an academic empire p33
David Joravsky
doi:10.1038/32083
Pairs of genes p34
John Galloway
doi:10.1038/32086
Underground revelations p35
doi:10.1038/32089
True stories p35
Stathis Psillos
doi:10.1038/32092
At a glance p36
Marlene Zuk and Steven Siller
doi:10.1038/32094
Hypothesis
The hydrogen hypothesis for the first eukaryote p37
William Martin and Miklós Müller
doi:10.1038/32096
Abstract | Full Text | PDF (245K)
See also: News and Views by Doolittle
Article
Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA p42
Lin Chen, J. N. Mark Glover, Patrick G. Hogan, Anjana Rao and Stephen C. Harrison
doi:10.1038/32100
Abstract | Full Text | PDF (880K)
Letters to Nature
Two distinct populations of Kuiper-belt objects p49
S. C. Tegler and W. Romanishin
doi:10.1038/32108
First paragraph | Full Text | PDF (231K)
See also: News and Views by Chapman
Subsurface charge accumulation imaging of a quantum Hall liquid p51
S. H. Tessmer, P. I. Glicofridis, R. C. Ashoori, L. S. Levitov and M. R. Melloch
doi:10.1038/32112
First paragraph | Full Text | PDF (1,792K)
Highly mobile electrons and holes on isolated chains of the semiconducting polymer poly(phenylene vinylene) p54
Romano J. O. M. Hoofman, Matthijs P. de Haas, Laurens D. A. Siebbeles and John M. Warman
doi:10.1038/32118
First paragraph | Full Text | PDF (232K)
Uniform quantum-dot arrays formed by natural self-faceting on patterned substrates p56
Richard Nötzel, Zhichuan Niu, Manfred Ramsteiner, Hans-Peter Schönherr, Achim Tranpert, Lutz Däweritz and Klaus H. Ploog
doi:10.1038/32127
First paragraph | Full Text | PDF (323K)
Atmospheric CO2 concentration and millennial-scale climate change during the last glacial period p59
B. Stauffer, T. Blunier, A. Dällenbach, A. Indermühle, J. Schwander, T. F. Stocker, J. Tschumi, J. Chappellaz, D. Raynaud, C. U. Hammer and H. B. Clausen
doi:10.1038/32133
First paragraph | Full Text | PDF (386K)
Influence of sea-salt on aerosol radiative properties in the Southern Ocean marine boundary layer p62
D. M. Murphy, J. R. Anderson, P. K. Quinn, L. M. McInnes, F. J. Brechtel, S. M. Kreidenweis, A. M. Middlebrook, M. Pósfai, D. S. Thomson and P. R. Buseck
doi:10.1038/32138
First paragraph | Full Text | PDF (278K)
Transition from dome-forming to plinian eruptive styles controlled by H2O and Cl degassing p65
Benoît Villemant and Georges Boudon
doi:10.1038/32144
First paragraph | Full Text | PDF (313K)
Selectivity of extinction among sea urchins at the end of the Cretaceous period p69
Andrew B. Smith and Charlotte H. Jeffery
doi:10.1038/32155
First paragraph | Full Text | PDF (235K)
See also: News and Views by Marshall
A molecular evolutionary framework for the phylum Nematoda p71
Mark L. Blaxter, Paul De Ley, James R. Garey, Leo X. Liu, Patsy Scheldeman, Andy Vierstraete, Jacques R. Vanfleteren, Laura Y. Mackey, Mark Dorris, Linda M. Frisse, J. T. Vida and W. Kelley Thomas
doi:10.1038/32160
First paragraph | Full Text | PDF (322K)
See also: News and Views by Nielsen
Spatial and temporal organization during cardiac fibrillation p75
Richard A. Gray, Arkady M. Pertsov and José Jalife
doi:10.1038/32164
First paragraph | Full Text | PDF (597K)
See also: News and Views by Holden
Spatiotemporal evolution of ventricular fibrillation p78
Francis X. Witkowski, L. Joshua Leon, Patricia A. Penkoske, Wayne R. Giles, Mark L. Spano, William L. Ditto and Arthur T. Winfree
doi:10.1038/32170
First paragraph | Full Text | PDF (885K) | Supplementary information
See also: News and Views by Holden
Synapse-specific control of synaptic efficacy at the terminals of a single neuron p82
Graeme W. Davis and Corey S. Goodman
doi:10.1038/32176
First paragraph | Full Text | PDF (333K)
Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs p86
Matthew L. Albert, Birthe Sauter and Nina Bhardwaj
doi:10.1038/32183
First paragraph | Full Text | PDF (315K)
Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites p90
Chris S. Lantz, Jurg Boesiger, Chang Ho Song, Nicolas Mach, Takahiko Kobayashi, Richard C. Mulligan, Yukifumi Nawa, Glenn Dranoff and Stephen J. Galli
doi:10.1038/32190
First paragraph | Full Text | PDF (357K)
Regulated nuclear import of Rel proteins in the Drosophila immune response p93
Louisa P. Wu and Kathryn V. Anderson
doi:10.1038/32195
First paragraph | Full Text | PDF (557K)
The 1.7 Å crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller p97
Louis Renault, Nicolas Nassar, Ingrid Vetter, Jörg Becker, Christian Klebe, Michel Roth and Alfred Wittinghofer
doi:10.1038/32204
First paragraph | Full Text | PDF (758K)
Structure of the Sec7 domain of the Arf exchange factor ARNO p101
Jacqueline Cherfils, Julie Ménétrey, Magali Mathieu, Gérard Le Bras, Sylviane Robineau, Sophie Béraud-Dufour, Bruno Antonny and Pierre Chardin
doi:10.1038/32210
First paragraph | Full Text | PDF (593K)
Erratum: Radical alterations in the roles of homeobox genes during echinoderm evolution p105
Christopher J. Lowe and Gregory A. Wray
doi:10.1038/32217
New on the Market
Antibodies and immunology p107
This group of products includes a collagen-based kit for identifying and quantifying megakaryocytic progenitors, flow cytometry reagents, an antigen retrieval kit and a permeabilization reagent to help detect intracellular antigens.
These notes are compiled by Brendan Horton from information provided by the manufacturers. For more details, fill in the reader service card bound inside the journal
doi:10.1038/32220
